node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PIIN_00279 | PIIN_00477 | G4T5H8 | G4U2M1 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.844 |
PIIN_00279 | PIIN_02102 | G4T5H8 | G4TA85 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Related to para-aminobenzoic acid synthetase. | 0.661 |
PIIN_00279 | PIIN_02310 | G4T5H8 | G4TAW2 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Uncharacterized protein. | 0.772 |
PIIN_00279 | PIIN_02366 | G4T5H8 | G4TB02 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities. | 0.727 |
PIIN_00279 | PIIN_02476 | G4T5H8 | G4TBC5 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.661 |
PIIN_00279 | PIIN_03416 | G4T5H8 | G4U2H2 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Probable TRP2-anthranilate synthase component I. | 0.610 |
PIIN_00279 | PIIN_05047 | G4T5H8 | G4TIH2 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Probable FOL2-GTP cyclohydrolase I. | 0.630 |
PIIN_00279 | PIIN_05753 | G4T5H8 | G4TKH5 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.661 |
PIIN_00279 | PIIN_07877 | G4T5H8 | G4TRI1 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Probable MIS1-C1-tetrahydrofolate synthase, mitochondrial. | 0.832 |
PIIN_00477 | PIIN_00279 | G4U2M1 | G4T5H8 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | 0.844 |
PIIN_00477 | PIIN_02102 | G4U2M1 | G4TA85 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | Related to para-aminobenzoic acid synthetase. | 0.461 |
PIIN_00477 | PIIN_02310 | G4U2M1 | G4TAW2 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | Uncharacterized protein. | 0.867 |
PIIN_00477 | PIIN_02366 | G4U2M1 | G4TB02 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities. | 0.941 |
PIIN_00477 | PIIN_02476 | G4U2M1 | G4TBC5 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.469 |
PIIN_00477 | PIIN_03416 | G4U2M1 | G4U2H2 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | Probable TRP2-anthranilate synthase component I. | 0.462 |
PIIN_00477 | PIIN_05047 | G4U2M1 | G4TIH2 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | Probable FOL2-GTP cyclohydrolase I. | 0.643 |
PIIN_00477 | PIIN_05753 | G4U2M1 | G4TKH5 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.469 |
PIIN_00477 | PIIN_07877 | G4U2M1 | G4TRI1 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | Probable MIS1-C1-tetrahydrofolate synthase, mitochondrial. | 0.965 |
PIIN_00477 | PIIN_08384 | G4U2M1 | G4TSY8 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | Related to glycinamide ribonucleotide transformylase. | 0.963 |
PIIN_02102 | PIIN_00279 | G4TA85 | G4T5H8 | Related to para-aminobenzoic acid synthetase. | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | 0.661 |