STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIIN_03514DNA polymerase. (1069 aa)    
Predicted Functional Partners:
PIIN_01107
Related to dna polymerase delta small subunit.
   
 0.999
PIIN_01285
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.997
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.992
PIIN_01755
Uncharacterized protein.
   
 0.991
PIIN_07650
DNA helicase; Belongs to the MCM family.
   
 0.989
PIIN_00724
DNA helicase; Belongs to the MCM family.
   
 0.985
PIIN_08962
Related to RAD27-ssDNA endonuclease and 5`-3`exonuclease.
   
 0.980
PIIN_07720
DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family.
   
 0.979
PIIN_02218
DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.
   
 0.978
PIIN_03502
Related to POL12 (DNA-directed DNA polymerase alpha).
   
 0.977
Your Current Organism:
Serendipita indica
NCBI taxonomy Id: 1109443
Other names: Piriformospora indica DSM 11827, S. indica DSM 11827, Serendipita indica DSM 11827
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