STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIIN_09692Related to MIP1-DNA-directed DNA polymerase gamma catalytic subunit, mitochondrial. (1447 aa)    
Predicted Functional Partners:
PIIN_04103
Related to probable RNA helicase MPH1.
   
 
 0.987
PIIN_07173
Probable glycine--tRNA ligase GRS1.
   
 
 0.932
PIIN_02676
Related to formamidopyrimidine-DNA glycosylase.
  
  
 0.868
PIIN_07813
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
   
 0.848
PIIN_11826
Probable RAD50-DNA repair protein.
   
 
 0.778
PIIN_06809
Related to MXR1-protein-methionine-s-oxide reductase.
   
  
 0.775
PIIN_01809
Uncharacterized protein.
   
 0.759
PIIN_00367
Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.
   
 
 0.750
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
  
 
 0.748
PIIN_06685
Related to dna excision repair protein ercc-1.
     
 0.745
Your Current Organism:
Serendipita indica
NCBI taxonomy Id: 1109443
Other names: Piriformospora indica DSM 11827, S. indica DSM 11827, Serendipita indica DSM 11827
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