STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMD88320.1MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (472 aa)    
Predicted Functional Partners:
AMD86481.1
Nitrate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
  
 0.599
AMD88319.1
Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.574
AMD87163.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.573
AMD86483.1
Nitrate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.502
narY
Nitrate reductase; With NarZV catalyzes the reduction of nitrate; the beta subunit is an iron sulfur cluster containing electron transfer subunit; one of 3 nitrate reductases in E. coli; expression of nitrate reductase Z is not dependent on nitrate levels; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.500
AMD86484.1
Nitrate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.474
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
       0.463
AMD87184.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
     0.462
AMD87914.1
Permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.403
Your Current Organism:
Actinomyces radicidentis
NCBI taxonomy Id: 111015
Other names: A. radicidentis, Actinomyces radicidentis Collins et al. 2001 emend. Nouioui et al. 2018, Actinomyces sp. CCUG 36733, Actinomyces sp. CCUG 36733T, CCUG 36733, CIP 106352, DSM 15433
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