STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (652 aa)    
Predicted Functional Partners:
citA
Citrate (Si)-synthase; Belongs to the citrate synthase family.
  
 0.948
prpC
2-methylcitrate synthase/citrate synthase II; Belongs to the citrate synthase family.
  
 0.948
gltA
Citrate synthase I; Belongs to the citrate synthase family.
  
 0.948
dhaS
Betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.934
acoD
Acetaldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.934
mmsA
Methylmalonate-semialdehyde dehydrogenase.
  
 0.933
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
   
 
 0.932
phaA
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.929
TMO_2578
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.929
TMO_0622
acetyl-CoA synthetase.
  
  
 
0.922
Your Current Organism:
Tistrella mobilis
NCBI taxonomy Id: 1110502
Other names: T. mobilis KA081020-065, Tistrella mobilis KA081020-065, Tistrella mobilis str. KA081020-065, Tistrella mobilis strain KA081020-065
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