node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
TMO_2432 | guaA | TMO_2432 | TMO_1445 | Putative 3-carboxy-cis,cis-muconate cycloisomerase (3-carboxymuconate lactonizing enzyme). | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 0.911 |
TMO_2432 | guaB | TMO_2432 | TMO_1438 | Putative 3-carboxy-cis,cis-muconate cycloisomerase (3-carboxymuconate lactonizing enzyme). | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.873 |
TMO_2432 | pcaC | TMO_2432 | TMO_2435 | Putative 3-carboxy-cis,cis-muconate cycloisomerase (3-carboxymuconate lactonizing enzyme). | 4-carboxymuconolactone decarboxylase. | 0.997 |
TMO_2432 | pcaD | TMO_2432 | TMO_2870 | Putative 3-carboxy-cis,cis-muconate cycloisomerase (3-carboxymuconate lactonizing enzyme). | Alpha/beta hydrolase fold protein. | 0.893 |
TMO_2432 | pcaG | TMO_2432 | TMO_2433 | Putative 3-carboxy-cis,cis-muconate cycloisomerase (3-carboxymuconate lactonizing enzyme). | Protocatechuate 3,4-dioxygenase, alpha subunit(PcaG). | 0.996 |
TMO_2432 | pcaH | TMO_2432 | TMO_2434 | Putative 3-carboxy-cis,cis-muconate cycloisomerase (3-carboxymuconate lactonizing enzyme). | Protocatechuate 3,4-dioxygenase, beta subunit. | 0.996 |
TMO_2432 | pobA | TMO_2432 | TMO_2431 | Putative 3-carboxy-cis,cis-muconate cycloisomerase (3-carboxymuconate lactonizing enzyme). | 4-hydroxybenzoate 3-monooxygenase. | 0.954 |
TMO_2432 | purA | TMO_2432 | TMO_0921 | Putative 3-carboxy-cis,cis-muconate cycloisomerase (3-carboxymuconate lactonizing enzyme). | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.912 |
TMO_2432 | purC | TMO_2432 | TMO_2257 | Putative 3-carboxy-cis,cis-muconate cycloisomerase (3-carboxymuconate lactonizing enzyme). | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.849 |
TMO_2432 | purF | TMO_2432 | TMO_1879 | Putative 3-carboxy-cis,cis-muconate cycloisomerase (3-carboxymuconate lactonizing enzyme). | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.848 |
guaA | TMO_2432 | TMO_1445 | TMO_2432 | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | Putative 3-carboxy-cis,cis-muconate cycloisomerase (3-carboxymuconate lactonizing enzyme). | 0.911 |
guaA | guaB | TMO_1445 | TMO_1438 | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
guaA | purA | TMO_1445 | TMO_0921 | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.963 |
guaA | purC | TMO_1445 | TMO_2257 | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.785 |
guaA | purF | TMO_1445 | TMO_1879 | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.854 |
guaB | TMO_2432 | TMO_1438 | TMO_2432 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Putative 3-carboxy-cis,cis-muconate cycloisomerase (3-carboxymuconate lactonizing enzyme). | 0.873 |
guaB | guaA | TMO_1438 | TMO_1445 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 0.999 |
guaB | purA | TMO_1438 | TMO_0921 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.996 |
guaB | purC | TMO_1438 | TMO_2257 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.790 |
guaB | purF | TMO_1438 | TMO_1879 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.917 |