TMO_2936 protein (Tistrella mobilis) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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Score

TMO_2936

Cobalt ABC transporter, inner membrane subunit CbiQ. (152 aa)

Predicted Functional Partners:

TMO_2934

0.999

cbiM

0.999

cbiN

0.995

TMO_2935

0.976

cobJ

0.807

bioY

0.724

bioY-2

0.724

cobL

0.682

yhiH-2

0.523

gsiA

0.499

Your Current Organism:

Tistrella mobilis

NCBI taxonomy Id: 1110502
Other names: T. mobilis KA081020-065, Tistrella mobilis KA081020-065, Tistrella mobilis str. KA081020-065, Tistrella mobilis strain KA081020-065

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
TMO_2934	TMO_2935	TMO_2934	TMO_2935	Cobalt transport protein ATP-binding subunit; Part of an ABC transporter complex. Responsible for energy coupling to the transport system.	Cobalt transport integral membrane protein.	0.997
TMO_2934	TMO_2936	TMO_2934	TMO_2936	Cobalt transport protein ATP-binding subunit; Part of an ABC transporter complex. Responsible for energy coupling to the transport system.	Cobalt ABC transporter, inner membrane subunit CbiQ.	0.999
TMO_2934	bioY	TMO_2934	TMO_0728	Cobalt transport protein ATP-binding subunit; Part of an ABC transporter complex. Responsible for energy coupling to the transport system.	Putative biotin transporter bioY.	0.832
TMO_2934	bioY-2	TMO_2934	TMO_2594	Cobalt transport protein ATP-binding subunit; Part of an ABC transporter complex. Responsible for energy coupling to the transport system.	Putative biotin transporter bioY.	0.832
TMO_2934	cbiM	TMO_2934	TMO_2938	Cobalt transport protein ATP-binding subunit; Part of an ABC transporter complex. Responsible for energy coupling to the transport system.	Cobalamin biosynthesis protein cbim; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.	0.998
TMO_2934	cbiN	TMO_2934	TMO_2937	Cobalt transport protein ATP-binding subunit; Part of an ABC transporter complex. Responsible for energy coupling to the transport system.	Cobalt transport protein; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import; Belongs to the CbiN family.	0.995
TMO_2934	cobJ	TMO_2934	TMO_2773	Cobalt transport protein ATP-binding subunit; Part of an ABC transporter complex. Responsible for energy coupling to the transport system.	precorrin-3B C17-methyltransferase (cobJ).	0.790
TMO_2934	cobL	TMO_2934	TMO_2775	Cobalt transport protein ATP-binding subunit; Part of an ABC transporter complex. Responsible for energy coupling to the transport system.	Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase.	0.674
TMO_2935	TMO_2934	TMO_2935	TMO_2934	Cobalt transport integral membrane protein.	Cobalt transport protein ATP-binding subunit; Part of an ABC transporter complex. Responsible for energy coupling to the transport system.	0.997
TMO_2935	TMO_2936	TMO_2935	TMO_2936	Cobalt transport integral membrane protein.	Cobalt ABC transporter, inner membrane subunit CbiQ.	0.976
TMO_2935	bioY	TMO_2935	TMO_0728	Cobalt transport integral membrane protein.	Putative biotin transporter bioY.	0.724
TMO_2935	bioY-2	TMO_2935	TMO_2594	Cobalt transport integral membrane protein.	Putative biotin transporter bioY.	0.724
TMO_2935	cbiM	TMO_2935	TMO_2938	Cobalt transport integral membrane protein.	Cobalamin biosynthesis protein cbim; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.	0.996
TMO_2935	cbiN	TMO_2935	TMO_2937	Cobalt transport integral membrane protein.	Cobalt transport protein; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import; Belongs to the CbiN family.	0.983
TMO_2935	cobJ	TMO_2935	TMO_2773	Cobalt transport integral membrane protein.	precorrin-3B C17-methyltransferase (cobJ).	0.807
TMO_2935	cobL	TMO_2935	TMO_2775	Cobalt transport integral membrane protein.	Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase.	0.682
TMO_2935	gsiA	TMO_2935	TMO_0273	Cobalt transport integral membrane protein.	ABC transporter ATP-binding protein; Belongs to the ABC transporter superfamily.	0.499
TMO_2935	yhiH-2	TMO_2935	TMO_3481	Cobalt transport integral membrane protein.	ABC transporter, ATP binding/permease protein.	0.523
TMO_2936	TMO_2934	TMO_2936	TMO_2934	Cobalt ABC transporter, inner membrane subunit CbiQ.	Cobalt transport protein ATP-binding subunit; Part of an ABC transporter complex. Responsible for energy coupling to the transport system.	0.999
TMO_2936	TMO_2935	TMO_2936	TMO_2935	Cobalt ABC transporter, inner membrane subunit CbiQ.	Cobalt transport integral membrane protein.	0.976

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Network Stats

number of nodes:

11

number of edges:

25

average node degree:

4.55

avg. local clustering coefficient:

0.885

expected number of edges:

10

PPI enrichment p-value:

7.38e-05

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003700

DNA-binding transcription factor activity

6 of 278

1.1

0.87

0.0022

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:6195

Glycoside hydrolase family 16, and Creatinase, N-terminal

4 of 5

2.67

3.24

8.80e-07

CL:8054

Mixed, incl. LytR_cpsA_psr family, and Thiazole synthase activity

2 of 6

2.29

1.03

0.0123

CL:8049

Mixed, incl. Nicotinate and nicotinamide metabolism, and Helix-turn-helix, HxlR type

3 of 46

1.58

0.91

0.0123

CL:7924

Mixed, incl. Sequence-specific DNA binding, and Nicotinate and nicotinamide metabolism

4 of 123

1.28

0.83

0.0102

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0805

Transcription regulation

6 of 453

0.89

0.6

0.0097

KW-0238

DNA-binding

6 of 523

0.82

0.56

0.0097

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR028978

Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily

3 of 3

2.76

2.11

0.00014

IPR011663

UbiC transcription regulator-associated

3 of 3

2.76

2.11

0.00014

IPR000524

Transcription regulator HTH, GntR

3 of 30

1.76

0.96

0.0123

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00866

The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain that has a similar fold to PUBMED:12757941. It is believed to modulate activity of bacterial transcription factors in response to binding small molecules.

2 of 2

2.76

1.44

0.0024

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