node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
TMO_2991 | priA | TMO_2991 | TMO_2989 | Hypothetical protein. | Primosome assembly protein PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.533 |
TMO_2991 | tal | TMO_2991 | TMO_2990 | Hypothetical protein. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | 0.732 |
TMO_2991 | xerC | TMO_2991 | TMO_2992 | Hypothetical protein. | Tyrosine recombinase xerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.849 |
apt | gntX | TMO_0990 | TMO_0358 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Phosphoribosyltransferase. | 0.722 |
apt | polA | TMO_0990 | TMO_3211 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.630 |
apt | tyrC | TMO_0990 | TMO_0139 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Cyclohexadienyl dehydrogenase. | 0.743 |
apt | xerC | TMO_0990 | TMO_2992 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Tyrosine recombinase xerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.525 |
ftsK | mfd | TMO_0403 | TMO_1627 | Cell division FtsK/SpoIIIE; Belongs to the FtsK/SpoIIIE/SftA family. | Transcription-repair coupling factor superfamily II helicase; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.509 |
ftsK | polA | TMO_0403 | TMO_3211 | Cell division FtsK/SpoIIIE; Belongs to the FtsK/SpoIIIE/SftA family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.640 |
ftsK | recR | TMO_0403 | TMO_2693 | Cell division FtsK/SpoIIIE; Belongs to the FtsK/SpoIIIE/SftA family. | Recombinational DNA repair protein (RecF pathway); May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.615 |
ftsK | xerC | TMO_0403 | TMO_2992 | Cell division FtsK/SpoIIIE; Belongs to the FtsK/SpoIIIE/SftA family. | Tyrosine recombinase xerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.539 |
gntX | apt | TMO_0358 | TMO_0990 | Phosphoribosyltransferase. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.722 |
gntX | tyrC | TMO_0358 | TMO_0139 | Phosphoribosyltransferase. | Cyclohexadienyl dehydrogenase. | 0.744 |
gntX | xerC | TMO_0358 | TMO_2992 | Phosphoribosyltransferase. | Tyrosine recombinase xerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.535 |
mfd | ftsK | TMO_1627 | TMO_0403 | Transcription-repair coupling factor superfamily II helicase; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Cell division FtsK/SpoIIIE; Belongs to the FtsK/SpoIIIE/SftA family. | 0.509 |
mfd | polA | TMO_1627 | TMO_3211 | Transcription-repair coupling factor superfamily II helicase; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.659 |
mfd | recR | TMO_1627 | TMO_2693 | Transcription-repair coupling factor superfamily II helicase; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Recombinational DNA repair protein (RecF pathway); May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.549 |
mfd | xerC | TMO_1627 | TMO_2992 | Transcription-repair coupling factor superfamily II helicase; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Tyrosine recombinase xerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.636 |
polA | apt | TMO_3211 | TMO_0990 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.630 |
polA | ftsK | TMO_3211 | TMO_0403 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Cell division FtsK/SpoIIIE; Belongs to the FtsK/SpoIIIE/SftA family. | 0.640 |