STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHK89055.1FMN adenylyltransferase /riboflavin kinase; COG0196 FAD synthase; Belongs to the ribF family. (313 aa)    
Predicted Functional Partners:
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
 
 
 0.987
ribBA
Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
 
  
 0.955
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
 
  
 0.951
EHK82262.1
COG0117 Pyrimidine deaminase.
  
 
 0.934
EHK82263.1
COG0307 Riboflavin synthase alpha chain.
  
 
 0.932
EHK88135.1
COG0431 Predicted flavoprotein.
    
 0.876
EHK86012.1
COG0431 Predicted flavoprotein.
    
 0.876
rpsO
30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
  
  
 0.813
EHK85229.1
COG1985 Pyrimidine reductase, riboflavin biosynthesis.
  
 
 0.802
cmk
COG0283 Cytidylate kinase.
 
  
 0.792
Your Current Organism:
Saccharomonospora azurea
NCBI taxonomy Id: 1114959
Other names: S. azurea SZMC 14600, Saccharomonospora azurea SZMC 14600, Saccharomonospora azurea str. SZMC 14600, Saccharomonospora azurea strain SZMC 14600
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