STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHK87214.1RimK domain-containing protein ATP-grasp. (152 aa)    
Predicted Functional Partners:
EHK84890.1
Glutamate synthase (NADPH/NADH) large chain; COG0067 Glutamate synthase domain 1.
    
 0.849
EHK87213.1
COG2518 Protein-L-isoaspartate carboxylmethyltransferase.
 
     0.593
secD
Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
    
 0.536
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
    
 0.511
pyrB
COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
    
 0.501
egtA
Glutamate--cysteine ligase GCS2; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine.
    
 0.496
EHK88172.1
Hypothetical protein.
    
 0.496
EHK88990.1
COG0405 Gamma-glutamyltransferase.
     
 0.474
EHK88660.1
COG0405 Gamma-glutamyltransferase.
     
 0.474
murF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
    
  0.474
Your Current Organism:
Saccharomonospora azurea
NCBI taxonomy Id: 1114959
Other names: S. azurea SZMC 14600, Saccharomonospora azurea SZMC 14600, Saccharomonospora azurea str. SZMC 14600, Saccharomonospora azurea strain SZMC 14600
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