STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ttcAtRNA 2-thiocytidine biosynthesis protein TtcA; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. (290 aa)    
Predicted Functional Partners:
gltB
Ferredoxin-dependent glutamate synthase 1.
    
  0.884
thiG
Thiazole synthase ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
  
   0.845
guaA-2
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.830
ESS70450.1
Hypothetical protein.
       0.682
ESS70451.1
Hypothetical protein.
       0.682
purH
Bifunctional purine biosynthesis protein PurH.
   
  0.609
wecB
UDP-N-acetylglucosamine 2-epimerase WecB; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
  
 
 0.599
ESS72713.1
Phosphoribosyltransferase.
  
 
 0.588
pth
peptidyl-tRNA hydrolase Pth; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
  
    0.528
mfd
Transcription-repair-coupling factor Mfd; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
  
    0.524
Your Current Organism:
Methyloglobulus morosus
NCBI taxonomy Id: 1116472
Other names: M. morosus KoM1, Methylococcaceae bacterium KoM1, Methyloglobulus morosus KoM1
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