STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ESS72951.15'-nucleotidase. (300 aa)    
Predicted Functional Partners:
guaB
Inosine-5'-monophosphate dehydrogenase GuaB; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
  0.922
ppnP
Hypothetical protein UPF0345; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.
     
  0.922
cpdA
3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
    
  0.851
ESS71527.1
Hypothetical protein.
  
     0.586
ESS72949.1
Alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen.
       0.534
ESS72950.1
Putative glycine cleavage system transcriptional repressor.
       0.534
ESS68085.1
Hopanoid-associated phosphorylase.
    
  0.421
ESS73654.1
Ion transport 2 domain-containing protein.
  
     0.408
Your Current Organism:
Methyloglobulus morosus
NCBI taxonomy Id: 1116472
Other names: M. morosus KoM1, Methylococcaceae bacterium KoM1, Methyloglobulus morosus KoM1
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