node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ERG53479.1 | ERG53482.1 | PSPO_10744 | PSPO_10759 | Hypothetical protein; COG0443 Molecular chaperone. | PLP-binding domain-containing protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.793 |
ERG53479.1 | ERG54913.1 | PSPO_10744 | PSPO_03907 | Hypothetical protein; COG0443 Molecular chaperone. | Lipoprotein; COG4805 Uncharacterized protein conserved in bacteria. | 0.610 |
ERG53479.1 | hemN | PSPO_10744 | PSPO_03912 | Hypothetical protein; COG0443 Molecular chaperone. | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.610 |
ERG53479.1 | pilT | PSPO_10744 | PSPO_10764 | Hypothetical protein; COG0443 Molecular chaperone. | Twitching motility protein PilT; COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT. | 0.745 |
ERG53479.1 | proC | PSPO_10744 | PSPO_10754 | Hypothetical protein; COG0443 Molecular chaperone. | Pyrroline-5-carboxylate reductase (NAD(P)-binding) protein; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.811 |
ERG53479.1 | rdgB | PSPO_10744 | PSPO_03917 | Hypothetical protein; COG0443 Molecular chaperone. | dITP/XTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.834 |
ERG53479.1 | yggT | PSPO_10744 | PSPO_10749 | Hypothetical protein; COG0443 Molecular chaperone. | COG0762 Predicted integral membrane protein. | 0.811 |
ERG53482.1 | ERG53479.1 | PSPO_10759 | PSPO_10744 | PLP-binding domain-containing protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Hypothetical protein; COG0443 Molecular chaperone. | 0.793 |
ERG53482.1 | ERG54913.1 | PSPO_10759 | PSPO_03907 | PLP-binding domain-containing protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Lipoprotein; COG4805 Uncharacterized protein conserved in bacteria. | 0.610 |
ERG53482.1 | hemN | PSPO_10759 | PSPO_03912 | PLP-binding domain-containing protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.751 |
ERG53482.1 | pilT | PSPO_10759 | PSPO_10764 | PLP-binding domain-containing protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Twitching motility protein PilT; COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT. | 0.822 |
ERG53482.1 | proC | PSPO_10759 | PSPO_10754 | PLP-binding domain-containing protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Pyrroline-5-carboxylate reductase (NAD(P)-binding) protein; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.928 |
ERG53482.1 | rdgB | PSPO_10759 | PSPO_03917 | PLP-binding domain-containing protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | dITP/XTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.709 |
ERG53482.1 | rlmN | PSPO_10759 | PSPO_02610 | PLP-binding domain-containing protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Ribosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.480 |
ERG53482.1 | yggT | PSPO_10759 | PSPO_10749 | PLP-binding domain-containing protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | COG0762 Predicted integral membrane protein. | 0.962 |
ERG54913.1 | ERG53479.1 | PSPO_03907 | PSPO_10744 | Lipoprotein; COG4805 Uncharacterized protein conserved in bacteria. | Hypothetical protein; COG0443 Molecular chaperone. | 0.610 |
ERG54913.1 | ERG53482.1 | PSPO_03907 | PSPO_10759 | Lipoprotein; COG4805 Uncharacterized protein conserved in bacteria. | PLP-binding domain-containing protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.610 |
ERG54913.1 | hemN | PSPO_03907 | PSPO_03912 | Lipoprotein; COG4805 Uncharacterized protein conserved in bacteria. | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.817 |
ERG54913.1 | pilT | PSPO_03907 | PSPO_10764 | Lipoprotein; COG4805 Uncharacterized protein conserved in bacteria. | Twitching motility protein PilT; COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT. | 0.456 |
ERG54913.1 | proC | PSPO_03907 | PSPO_10754 | Lipoprotein; COG4805 Uncharacterized protein conserved in bacteria. | Pyrroline-5-carboxylate reductase (NAD(P)-binding) protein; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.610 |