| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| M5M_01745 | M5M_09400 | M5M_01745 | M5M_09400 | COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains). | COG0739 Membrane proteins related to metalloendopeptidases. | 0.499 |
| M5M_01745 | amiC | M5M_01745 | M5M_15335 | COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains). | COG0860 N-acetylmuramoyl-L-alanine amidase. | 0.502 |
| M5M_03335 | M5M_09400 | M5M_03335 | M5M_09400 | COG0681 Signal peptidase I; Belongs to the peptidase S26 family. | COG0739 Membrane proteins related to metalloendopeptidases. | 0.533 |
| M5M_09400 | M5M_01745 | M5M_09400 | M5M_01745 | COG0739 Membrane proteins related to metalloendopeptidases. | COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains). | 0.499 |
| M5M_09400 | M5M_03335 | M5M_09400 | M5M_03335 | COG0739 Membrane proteins related to metalloendopeptidases. | COG0681 Signal peptidase I; Belongs to the peptidase S26 family. | 0.533 |
| M5M_09400 | M5M_09410 | M5M_09400 | M5M_09410 | COG0739 Membrane proteins related to metalloendopeptidases. | Hypothetical protein. | 0.539 |
| M5M_09400 | M5M_11655 | M5M_09400 | M5M_11655 | COG0739 Membrane proteins related to metalloendopeptidases. | High-affinity zinc uptake system protein ZnuA; COG4531 ABC-type Zn2+ transport system, periplasmic component/surface adhesin. | 0.704 |
| M5M_09400 | M5M_14310 | M5M_09400 | M5M_14310 | COG0739 Membrane proteins related to metalloendopeptidases. | ATPase; COG4942 Membrane-bound metallopeptidase. | 0.732 |
| M5M_09400 | M5M_14717 | M5M_09400 | M5M_14717 | COG0739 Membrane proteins related to metalloendopeptidases. | COG5009 Membrane carboxypeptidase/penicillin-binding protein. | 0.511 |
| M5M_09400 | amiC | M5M_09400 | M5M_15335 | COG0739 Membrane proteins related to metalloendopeptidases. | COG0860 N-acetylmuramoyl-L-alanine amidase. | 0.758 |
| M5M_09400 | anmK | M5M_09400 | M5M_07540 | COG0739 Membrane proteins related to metalloendopeptidases. | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.500 |
| M5M_09400 | anmK-2 | M5M_09400 | M5M_09405 | COG0739 Membrane proteins related to metalloendopeptidases. | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.881 |
| M5M_09400 | tyrS | M5M_09400 | M5M_09395 | COG0739 Membrane proteins related to metalloendopeptidases. | tyrosyl-tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. | 0.636 |
| M5M_09410 | M5M_09400 | M5M_09410 | M5M_09400 | Hypothetical protein. | COG0739 Membrane proteins related to metalloendopeptidases. | 0.539 |
| M5M_09410 | anmK-2 | M5M_09410 | M5M_09405 | Hypothetical protein. | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.538 |
| M5M_09410 | tyrS | M5M_09410 | M5M_09395 | Hypothetical protein. | tyrosyl-tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. | 0.403 |
| M5M_11655 | M5M_09400 | M5M_11655 | M5M_09400 | High-affinity zinc uptake system protein ZnuA; COG4531 ABC-type Zn2+ transport system, periplasmic component/surface adhesin. | COG0739 Membrane proteins related to metalloendopeptidases. | 0.704 |
| M5M_14310 | M5M_09400 | M5M_14310 | M5M_09400 | ATPase; COG4942 Membrane-bound metallopeptidase. | COG0739 Membrane proteins related to metalloendopeptidases. | 0.732 |
| M5M_14310 | M5M_14717 | M5M_14310 | M5M_14717 | ATPase; COG4942 Membrane-bound metallopeptidase. | COG5009 Membrane carboxypeptidase/penicillin-binding protein. | 0.537 |
| M5M_14310 | amiC | M5M_14310 | M5M_15335 | ATPase; COG4942 Membrane-bound metallopeptidase. | COG0860 N-acetylmuramoyl-L-alanine amidase. | 0.863 |
