| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| M5M_00720 | M5M_09410 | M5M_00720 | M5M_09410 | Segregation and condensation protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | Hypothetical protein. | 0.528 |
| M5M_06320 | M5M_09410 | M5M_06320 | M5M_09410 | Endo-chitinase chi18D; COG3979 Uncharacterized protein contain chitin-binding domain type 3. | Hypothetical protein. | 0.627 |
| M5M_09400 | M5M_09410 | M5M_09400 | M5M_09410 | COG0739 Membrane proteins related to metalloendopeptidases. | Hypothetical protein. | 0.539 |
| M5M_09400 | anmK-2 | M5M_09400 | M5M_09405 | COG0739 Membrane proteins related to metalloendopeptidases. | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.881 |
| M5M_09400 | tyrS | M5M_09400 | M5M_09395 | COG0739 Membrane proteins related to metalloendopeptidases. | tyrosyl-tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. | 0.636 |
| M5M_09410 | M5M_00720 | M5M_09410 | M5M_00720 | Hypothetical protein. | Segregation and condensation protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | 0.528 |
| M5M_09410 | M5M_06320 | M5M_09410 | M5M_06320 | Hypothetical protein. | Endo-chitinase chi18D; COG3979 Uncharacterized protein contain chitin-binding domain type 3. | 0.627 |
| M5M_09410 | M5M_09400 | M5M_09410 | M5M_09400 | Hypothetical protein. | COG0739 Membrane proteins related to metalloendopeptidases. | 0.539 |
| M5M_09410 | M5M_11210 | M5M_09410 | M5M_11210 | Hypothetical protein. | COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein. | 0.425 |
| M5M_09410 | M5M_16000 | M5M_09410 | M5M_16000 | Hypothetical protein. | Histone deacetylase/AcuC/AphA family protein; COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein. | 0.425 |
| M5M_09410 | anmK-2 | M5M_09410 | M5M_09405 | Hypothetical protein. | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.538 |
| M5M_09410 | gyrB | M5M_09410 | M5M_12427 | Hypothetical protein. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.454 |
| M5M_09410 | parE | M5M_09410 | M5M_11105 | Hypothetical protein. | DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. | 0.454 |
| M5M_09410 | topA | M5M_09410 | M5M_01135 | Hypothetical protein. | DNA topoisomerase I subunit omega; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus rem [...] | 0.439 |
| M5M_09410 | tyrS | M5M_09410 | M5M_09395 | Hypothetical protein. | tyrosyl-tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. | 0.403 |
| M5M_11210 | M5M_09410 | M5M_11210 | M5M_09410 | COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein. | Hypothetical protein. | 0.425 |
| M5M_16000 | M5M_09410 | M5M_16000 | M5M_09410 | Histone deacetylase/AcuC/AphA family protein; COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein. | Hypothetical protein. | 0.425 |
| anmK-2 | M5M_09400 | M5M_09405 | M5M_09400 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | COG0739 Membrane proteins related to metalloendopeptidases. | 0.881 |
| anmK-2 | M5M_09410 | M5M_09405 | M5M_09410 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Hypothetical protein. | 0.538 |
| anmK-2 | tyrS | M5M_09405 | M5M_09395 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | tyrosyl-tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. | 0.545 |
