STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
M5M_16405Hypothetical protein; Belongs to the Cob(I)alamin adenosyltransferase family. (188 aa)    
Predicted Functional Partners:
M5M_14555
cob(I)alamin adenolsyltransferase/cobinamide ATP-dependent adenolsyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.
    
 0.936
cobS
Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
    
 0.925
cobU
Adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.
    
 0.925
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
 
 0.920
M5M_16400
Hypothetical protein; COG0702 Predicted nucleoside-diphosphate-sugar epimerases.
  
    0.778
M5M_16410
Rieske (2Fe-2S) domain-containing protein; COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.
       0.732
M5M_16415
Hypothetical protein.
       0.732
M5M_16420
COG1541 Coenzyme F390 synthetase.
       0.732
M5M_16425
Metallo-beta-lactamase domain-containing protein; COG0491 Zn-dependent hydrolases, including glyoxylases.
       0.732
M5M_16430
NAD dependent epimerase/dehydratase; COG0451 Nucleoside-diphosphate-sugar epimerases.
       0.732
Your Current Organism:
Simiduia agarivorans
NCBI taxonomy Id: 1117647
Other names: S. agarivorans SA1 = DSM 21679, Simiduia agarivorans DSM 21679, Simiduia agarivorans DSM 21679 = SA1, Simiduia agarivorans SA1, Simiduia agarivorans SA1 = DSM 21679
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