node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFZ34160.1 | AFZ34217.1 | Sta7437_0559 | Sta7437_0619 | Serine O-acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: serine O-acetyltransferase; COGs: COG1045 Serine acetyltransferase; InterPro IPR001451:IPR005881; KEGG: cyc:PCC7424_3701 serine O-acetyltransferase; PFAM: Bacterial transferase hexapeptide repeat; PRIAM: Serine O-acetyltransferase; SPTR: Serine O-acetyltransferase; TIGRFAM: Serine O-acetyltransferase. | PFAM: Phosphoglycerate mutase family; COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: mar:MAE_05990 phosphoglycerate mutase; PFAM: Histidine phosphatase superfamily, clade-1; SPTR: Genome sequencing data, contig C304. | 0.800 |
AFZ34160.1 | AFZ36548.1 | Sta7437_0559 | Sta7437_3030 | Serine O-acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: serine O-acetyltransferase; COGs: COG1045 Serine acetyltransferase; InterPro IPR001451:IPR005881; KEGG: cyc:PCC7424_3701 serine O-acetyltransferase; PFAM: Bacterial transferase hexapeptide repeat; PRIAM: Serine O-acetyltransferase; SPTR: Serine O-acetyltransferase; TIGRFAM: Serine O-acetyltransferase. | Alanine-glyoxylate aminotransferase apoenzyme; PFAM: Aminotransferase class-V; COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR000192; KEGG: cyc:PCC7424_5094 aminotransferase class V; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Serine--pyruvate transaminase; SPTR: Aminotransferase class V. | 0.800 |
AFZ34160.1 | AFZ37729.1 | Sta7437_0559 | Sta7437_4256 | Serine O-acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: serine O-acetyltransferase; COGs: COG1045 Serine acetyltransferase; InterPro IPR001451:IPR005881; KEGG: cyc:PCC7424_3701 serine O-acetyltransferase; PFAM: Bacterial transferase hexapeptide repeat; PRIAM: Serine O-acetyltransferase; SPTR: Serine O-acetyltransferase; TIGRFAM: Serine O-acetyltransferase. | Threonine dehydratase; PFAM: ACT domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine dehydratase, medium form; COGs: COG1171 Threonine dehydratase; InterPro IPR005789:IPR001926:IPR002912; KEGG: nhl:Nhal_3584 threonine dehydratase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; Amino acid-binding ACT; SPTR: Threonine dehydratase; TIGRFAM: Threonine dehydratase II. | 0.806 |
AFZ34160.1 | glyA | Sta7437_0559 | Sta7437_3597 | Serine O-acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: serine O-acetyltransferase; COGs: COG1045 Serine acetyltransferase; InterPro IPR001451:IPR005881; KEGG: cyc:PCC7424_3701 serine O-acetyltransferase; PFAM: Bacterial transferase hexapeptide repeat; PRIAM: Serine O-acetyltransferase; SPTR: Serine O-acetyltransferase; TIGRFAM: Serine O-acetyltransferase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.833 |
AFZ34160.1 | ilvA | Sta7437_0559 | Sta7437_3390 | Serine O-acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: serine O-acetyltransferase; COGs: COG1045 Serine acetyltransferase; InterPro IPR001451:IPR005881; KEGG: cyc:PCC7424_3701 serine O-acetyltransferase; PFAM: Bacterial transferase hexapeptide repeat; PRIAM: Serine O-acetyltransferase; SPTR: Serine O-acetyltransferase; TIGRFAM: Serine O-acetyltransferase. | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.803 |
AFZ34160.1 | trpA | Sta7437_0559 | Sta7437_2033 | Serine O-acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: serine O-acetyltransferase; COGs: COG1045 Serine acetyltransferase; InterPro IPR001451:IPR005881; KEGG: cyc:PCC7424_3701 serine O-acetyltransferase; PFAM: Bacterial transferase hexapeptide repeat; PRIAM: Serine O-acetyltransferase; SPTR: Serine O-acetyltransferase; TIGRFAM: Serine O-acetyltransferase. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.810 |
AFZ34160.1 | trpB | Sta7437_0559 | Sta7437_2968 | Serine O-acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: serine O-acetyltransferase; COGs: COG1045 Serine acetyltransferase; InterPro IPR001451:IPR005881; KEGG: cyc:PCC7424_3701 serine O-acetyltransferase; PFAM: Bacterial transferase hexapeptide repeat; PRIAM: Serine O-acetyltransferase; SPTR: Serine O-acetyltransferase; TIGRFAM: Serine O-acetyltransferase. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.810 |
AFZ34217.1 | AFZ34160.1 | Sta7437_0619 | Sta7437_0559 | PFAM: Phosphoglycerate mutase family; COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: mar:MAE_05990 phosphoglycerate mutase; PFAM: Histidine phosphatase superfamily, clade-1; SPTR: Genome sequencing data, contig C304. | Serine O-acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: serine O-acetyltransferase; COGs: COG1045 Serine acetyltransferase; InterPro IPR001451:IPR005881; KEGG: cyc:PCC7424_3701 serine O-acetyltransferase; PFAM: Bacterial transferase hexapeptide repeat; PRIAM: Serine O-acetyltransferase; SPTR: Serine O-acetyltransferase; TIGRFAM: Serine O-acetyltransferase. | 0.800 |
AFZ34217.1 | AFZ34742.1 | Sta7437_0619 | Sta7437_1171 | PFAM: Phosphoglycerate mutase family; COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: mar:MAE_05990 phosphoglycerate mutase; PFAM: Histidine phosphatase superfamily, clade-1; SPTR: Genome sequencing data, contig C304. | Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 0.913 |
AFZ34217.1 | AFZ36548.1 | Sta7437_0619 | Sta7437_3030 | PFAM: Phosphoglycerate mutase family; COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: mar:MAE_05990 phosphoglycerate mutase; PFAM: Histidine phosphatase superfamily, clade-1; SPTR: Genome sequencing data, contig C304. | Alanine-glyoxylate aminotransferase apoenzyme; PFAM: Aminotransferase class-V; COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR000192; KEGG: cyc:PCC7424_5094 aminotransferase class V; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Serine--pyruvate transaminase; SPTR: Aminotransferase class V. | 0.908 |
AFZ34217.1 | AFZ36772.1 | Sta7437_0619 | Sta7437_3265 | PFAM: Phosphoglycerate mutase family; COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: mar:MAE_05990 phosphoglycerate mutase; PFAM: Histidine phosphatase superfamily, clade-1; SPTR: Genome sequencing data, contig C304. | Cobalt-precorrin 5A acetaldehyde-lyase; PFAM: Cobalamin biosynthesis central region; Cobalamin synthesis G C-terminus; Tetrapyrrole (Corrin/Porphyrin) Methylases; Cobalamin synthesis G N-terminal; TIGRFAM: precorrin-3B C17-methyltransferase; COGs: COG1010 Precorrin-3B methylase; InterPro IPR006363:IPR002750:IPR000878; KEGG: cyp:PCC8801_3628 precorrin-3B C17-methyltransferase; PFAM: Cobalamin (vitamin B12) biosynthesis CbiG, core; Tetrapyrrole methylase; PRIAM: Precorrin-3B C(17)-methyltransferase; SPTR: Precorrin-3B C17-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis C [...] | 0.549 |
AFZ34217.1 | AFZ37729.1 | Sta7437_0619 | Sta7437_4256 | PFAM: Phosphoglycerate mutase family; COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: mar:MAE_05990 phosphoglycerate mutase; PFAM: Histidine phosphatase superfamily, clade-1; SPTR: Genome sequencing data, contig C304. | Threonine dehydratase; PFAM: ACT domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine dehydratase, medium form; COGs: COG1171 Threonine dehydratase; InterPro IPR005789:IPR001926:IPR002912; KEGG: nhl:Nhal_3584 threonine dehydratase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; Amino acid-binding ACT; SPTR: Threonine dehydratase; TIGRFAM: Threonine dehydratase II. | 0.900 |
AFZ34217.1 | cobQ | Sta7437_0619 | Sta7437_3979 | PFAM: Phosphoglycerate mutase family; COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: mar:MAE_05990 phosphoglycerate mutase; PFAM: Histidine phosphatase superfamily, clade-1; SPTR: Genome sequencing data, contig C304. | Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.492 |
AFZ34217.1 | glyA | Sta7437_0619 | Sta7437_3597 | PFAM: Phosphoglycerate mutase family; COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: mar:MAE_05990 phosphoglycerate mutase; PFAM: Histidine phosphatase superfamily, clade-1; SPTR: Genome sequencing data, contig C304. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.920 |
AFZ34217.1 | ilvA | Sta7437_0619 | Sta7437_3390 | PFAM: Phosphoglycerate mutase family; COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: mar:MAE_05990 phosphoglycerate mutase; PFAM: Histidine phosphatase superfamily, clade-1; SPTR: Genome sequencing data, contig C304. | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.900 |
AFZ34217.1 | trpA | Sta7437_0619 | Sta7437_2033 | PFAM: Phosphoglycerate mutase family; COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: mar:MAE_05990 phosphoglycerate mutase; PFAM: Histidine phosphatase superfamily, clade-1; SPTR: Genome sequencing data, contig C304. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.900 |
AFZ34217.1 | trpB | Sta7437_0619 | Sta7437_2968 | PFAM: Phosphoglycerate mutase family; COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: mar:MAE_05990 phosphoglycerate mutase; PFAM: Histidine phosphatase superfamily, clade-1; SPTR: Genome sequencing data, contig C304. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.900 |
AFZ34742.1 | AFZ34217.1 | Sta7437_1171 | Sta7437_0619 | Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | PFAM: Phosphoglycerate mutase family; COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: mar:MAE_05990 phosphoglycerate mutase; PFAM: Histidine phosphatase superfamily, clade-1; SPTR: Genome sequencing data, contig C304. | 0.913 |
AFZ34742.1 | glyA | Sta7437_1171 | Sta7437_3597 | Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.624 |
AFZ36548.1 | AFZ34160.1 | Sta7437_3030 | Sta7437_0559 | Alanine-glyoxylate aminotransferase apoenzyme; PFAM: Aminotransferase class-V; COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR000192; KEGG: cyc:PCC7424_5094 aminotransferase class V; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Serine--pyruvate transaminase; SPTR: Aminotransferase class V. | Serine O-acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: serine O-acetyltransferase; COGs: COG1045 Serine acetyltransferase; InterPro IPR001451:IPR005881; KEGG: cyc:PCC7424_3701 serine O-acetyltransferase; PFAM: Bacterial transferase hexapeptide repeat; PRIAM: Serine O-acetyltransferase; SPTR: Serine O-acetyltransferase; TIGRFAM: Serine O-acetyltransferase. | 0.800 |