STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ34348.1PFAM: Response regulator receiver domain; Stage II sporulation protein E (SpoIIE); COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR001789:IPR001932:IPR010822; KEGG: cyt:cce_3320 two-component response regulator; PFAM: Sporulation stage II, protein E C-terminal; Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; Protein phosphatase 2C-related; SPTR: Two-component response regulator. (379 aa)    
Predicted Functional Partners:
AFZ34349.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; COGs: COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); KEGG: cyt:cce_3319 hypothetical protein; SPTR: Putative uncharacterized protein.
 
 
 0.922
AFZ36588.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; COGs: COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); InterPro IPR003594; KEGG: cyh:Cyan8802_1593 putative anti-sigma regulatory factor, serine/threonine protein kinase; PFAM: ATPase-like, ATP-binding domain; SPTR: Putative anti-sigma regulatory factor, serine/threonine protein kinase.
 
 
 0.856
AFZ34345.1
Anti-sigma-factor antagonist; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; COGs: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); InterPro IPR003658:IPR002645; KEGG: mar:MAE_59050 anti-sigma-factor antagonist; PFAM: Sulphate transporter/antisigma-factor antagonist STAS; SPTR: Anti-sigma factor antagonist; TIGRFAM: Anti-sigma factor antagonist.
 
 
 0.805
AFZ36792.1
Anti-sigma-factor antagonist; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; COGs: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); InterPro IPR003658:IPR002645; KEGG: cyc:PCC7424_0388 anti-sigma-factor antagonist; PFAM: Sulphate transporter/antisigma-factor antagonist STAS; SPTR: Anti-sigma factor antagonist; TIGRFAM: Anti-sigma factor antagonist.
 
 
 0.735
AFZ37894.1
CheA signal transduction histidine kinase; PFAM: CheW-like domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; Signal transducing histidine kinase, homodimeric domain; Hpt domain; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR008207:IPR004105:IPR003594:IPR002545:IPR 001789; KEGG: cyt:cce_4317 CheA signal transduction histidine kinase; PFAM: Signal transduction response regulator, receiver domain; ATPase-like, ATP-binding domain; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; Signal [...]
  
  
0.729
AFZ34108.1
Hypothetical protein; PFAM: Retroviral aspartyl protease; KEGG: cyt:cce_1720 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.728
AFZ34853.1
Multi-component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal; Hpt domain; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867:IPR008207; KEGG: npu:Npun_R3078 multi-component transcriptional regulator; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; SMART: Signal transducti [...]
 
  
0.717
AFZ34342.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain; GGDEF domain; PAS fold; FHA domain; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG2200 FOG: EAL domain; InterPro IPR000014:IPR000160:IPR000253:IPR001633; KEGG: cyt:cce_4177 hypothetical protein; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; Forkhead-associated; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; Forkhead-associated; PAS; SPTR: Putative uncharacterized protein; TIGRFAM: Diguanylate cyclase, predicted; PAS.
 
  
 0.708
AFZ36589.1
Anti-sigma-factor antagonist and sugar transfersase; PFAM: Bacterial sugar transferase; STAS domain; TIGRFAM: anti-anti-sigma factor; COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR003658:IPR002645:IPR003362; KEGG: cyh:Cyan8802_1592 anti-sigma-factor antagonist and sugar transfersase; PFAM: Bacterial sugar transferase; Sulphate transporter/antisigma-factor antagonist STAS; PRIAM: Undecaprenyl-phosphate galactose phosphotransferase; SPTR: Anti-sigma factor antagonist; TIGRFAM: Anti-sigma factor antagonist.
  
 
 0.672
AFZ34033.1
Diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: cyh:Cyan8802_0541 diguanylate cyclase; PFAM: Diguanylate cyclase, predicted; SMART: Diguanylate cyclase, predicted; SPTR: Diguanylate cyclase; TIGRFAM: Diguanylate cyclase, predicted.
 
 
    0.663
Your Current Organism:
Stanieria cyanosphaera
NCBI taxonomy Id: 111780
Other names: Dermocarpa sp. PCC 7437, S. cyanosphaera PCC 7437, Stanieria cyanosphaera PCC 7437, Stanieria cyanosphaera str. PCC 7437, Stanieria sp. ATCC 29371, Stanieria sp. PCC 7437
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