STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
mutLDNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (557 aa)    
Predicted Functional Partners:
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
 
 0.999
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 0.972
AFZ36800.1
PFAM: DNA polymerase III beta subunit, C-terminal domain; DNA polymerase III beta subunit, N-terminal domain; DNA polymerase III beta subunit, central domain; TIGRFAM: DNA polymerase III, beta subunit; COGs: COG0592 DNA polymerase sliding clamp subunit (PCNA homolog); InterPro IPR001001; KEGG: cyc:PCC7424_0340 DNA polymerase III subunit beta; PFAM: DNA polymerase III, beta chain; PRIAM: DNA-directed DNA polymerase; SMART: DNA polymerase III, beta chain; SPTR: DNA polymerase III, beta subunit; TIGRFAM: DNA polymerase III, beta chain.
   
 0.920
AFZ35462.1
ATP-dependent DNA helicase, RecQ family; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family; COGs: COG0514 Superfamily II DNA helicase; InterPro IPR011545:IPR001650:IPR018329:IPR014001; KEGG: cyc:PCC7424_1034 ATP-dependent DNA helicase, RecQ family; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; SPTR: ATP-dependent DNA helicase, RecQ family; TIGRFAM: DNA helicase, ATP-dependent, RecQ type, N-terminal.
  
 0.838
AFZ36733.1
ATP-dependent DNA helicase RecQ; PFAM: Helicase conserved C-terminal domain; RQC domain; HRDC domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase RecQ; ATP-dependent DNA helicase, RecQ family; COGs: COG0514 Superfamily II DNA helicase; InterProIPR006293:IPR018329:IPR014001:IPR001650:IPR 002121:IPR011545:IPR018982; KEGG: cyh:Cyan8802_1065 ATP-dependent DNA helicase RecQ; PFAM: RQC domain; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; Helicase/RNase D C-terminal, HRDC domain; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-term [...]
  
 0.837
mutS2
MutS2 protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
 
  
 0.747
miaA
tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
  
 0.741
AFZ36218.1
PFAM: Protein of unknown function (DUF2466); TIGRFAM: DNA repair protein radc; COGs: COG2003 DNA repair protein; InterPro IPR001405; KEGG: cyh:Cyan8802_0400 DNA repair protein RadC; PFAM: Uncharacterised protein family, RadC-like; SPTR: DNA repair protein RadC; TIGRFAM: Uncharacterised protein family, RadC-like; Belongs to the UPF0758 family.
 
   
 0.733
AFZ35442.1
KEGG: cyc:PCC7424_3670 hypothetical protein; SPTR: Putative uncharacterized protein.
 
 
 
 0.718
AFZ34969.1
PFAM: UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212; KEGG: cyc:PCC7424_4965 UvrD/REP helicase; PFAM: DNA helicase, UvrD/REP type; SPTR: UvrD/REP helicase.
 
 
 
 0.685
Your Current Organism:
Stanieria cyanosphaera
NCBI taxonomy Id: 111780
Other names: Dermocarpa sp. PCC 7437, S. cyanosphaera PCC 7437, Stanieria cyanosphaera PCC 7437, Stanieria cyanosphaera str. PCC 7437, Stanieria sp. ATCC 29371, Stanieria sp. PCC 7437
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