STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ34584.1PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR003495:IPR004392; KEGG: cyc:PCC7424_5247 hydrogenase accessory protein HypB; PFAM: Cobalamin (vitamin B12) biosynthesis CobW-like; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: Hydrogenase accessory protein HypB. (231 aa)    
Predicted Functional Partners:
hypA
Hydrogenase-3 nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.973
ureF
Urease accessory protein ureF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
  
 
 0.946
ureE
Urease accessory protein ureE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
  
 
 0.842
ureD
Urease accessory protein ureD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
  
 
 0.783
ureC
Urease subunit alpha; PFAM: Amidohydrolase family; Urease alpha-subunit, N-terminal domain; TIGRFAM: urease, alpha subunit; COGs: COG0804 Urea amidohydrolase (urease) alpha subunit; HAMAP: Urease, alpha subunit; InterPro IPR005848:IPR011612:IPR006680; KEGG: ter:Tery_0752 urease subunit alpha; PFAM: Amidohydrolase 1; Urease alpha-subunit, N-terminal; PRIAM: Urease; SPTR: Urease subunit alpha; TIGRFAM: Urease, alpha subunit.
  
  
 0.727
ureA
PFAM: Urease, gamma subunit; TIGRFAM: urease, gamma subunit; COGs: COG0831 Urea amidohydrolase (urease) gamma subunit; HAMAP: Urease, gamma subunit; InterPro IPR012010:IPR002026; KEGG: ava:Ava_3621 urease subunit gamma; PFAM: Urease, alpha/gamma subunit; PRIAM: Urease; SPTR: Urease subunit gamma; TIGRFAM: Urease, alpha/gamma subunit; Belongs to the urease gamma subunit family.
  
  
 0.726
ureB
PFAM: Urease beta subunit; TIGRFAM: urease, beta subunit; COGs: COG0832 Urea amidohydrolase (urease) beta subunit; HAMAP: Urease, beta subunit; InterPro IPR002019; KEGG: ter:Tery_0747 urease subunit beta; PFAM: Urease, beta subunit; PRIAM: Urease; SPTR: Urease subunit beta; TIGRFAM: Urease, beta subunit; Belongs to the urease beta subunit family.
  
  
 0.650
AFZ35812.1
Hypothetical protein; COGs: COG3259 Coenzyme F420-reducing hydrogenase alpha subunit; KEGG: cyt:cce_2315 hydrogenase large subunit; SPTR: Hydrogenase large subunit.
 
   
 0.556
AFZ34583.1
PFAM: NMT1/THI5 like; TIGRFAM: ABC transporter, substrate-binding protein, aliphatic sulfonates family; COGs: COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components; InterPro IPR010067; KEGG: cyn:Cyan7425_3256 aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein; SPTR: Aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein; TIGRFAM: ABC transporter, substrate-binding protein, aliphatic sulphonates.
     
 0.519
AFZ34582.1
PFAM: Binding-protein-dependent transport system inner membrane component; COGs: COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system permease component; InterPro IPR000515; KEGG: cyn:Cyan7425_3255 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component.
     
 0.441
Your Current Organism:
Stanieria cyanosphaera
NCBI taxonomy Id: 111780
Other names: Dermocarpa sp. PCC 7437, S. cyanosphaera PCC 7437, Stanieria cyanosphaera PCC 7437, Stanieria cyanosphaera str. PCC 7437, Stanieria sp. ATCC 29371, Stanieria sp. PCC 7437
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