STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
AFZ34614.1CheA signal transduction histidine kinase; PFAM: CheW-like domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; Signal transducing histidine kinase, homodimeric domain; Hpt domain; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterPro IPR008207:IPR003594:IPR002545:IPR001789; KEGG: amr:AM1_5077 CheA signal transduction histidine kinase; PFAM: Signal transduction response regulator, receiver domain; ATPase-like, ATP-binding domain; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; CheW-like protein [...] (775 aa)    
Predicted Functional Partners:
AFZ36927.1
Methyl-accepting chemotaxis sensory transducer with Cache sensor; PFAM: Cache domain; HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain; COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004010:IPR003660:IPR004089; KEGG: cyn:Cyan7425_1425 methyl-accepting chemotaxis sensory transducer; PFAM: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; Cache; SMART: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SPTR: Methyl-accepting chemotaxis sensory transducer.
 
 
 0.990
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 0.988
AFZ34617.1
PFAM: CheW-like domain; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: cyh:Cyan8802_0793 CheW protein; PFAM: CheW-like protein; SMART: CheW-like protein; SPTR: Chemotaxis signal transduction protein.
 
 
 0.984
AFZ34098.1
PAS/PAC sensor hybrid histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003661:IPR003594:IPR001789:IPR013656:IPR 013655:IPR000014:IPR001610; KEGG: npu:Npun_F2908 multi-sensor hybrid histidine kinase; PFAM: Signal transduction response regulator, receiver domain; ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS [...]
  
 
0.983
AFZ34615.1
PFAM: Methyl-accepting chemotaxis protein (MCP) signaling domain; COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089; KEGG: cyp:PCC8801_0762 methyl-accepting chemotaxis sensory transducer; PFAM: Chemotaxis methyl-accepting receptor, signalling; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: Methyl-accepting chemotaxis protein.
 
 
 0.983
AFZ37053.1
PFAM: HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain; COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089; KEGG: cyc:PCC7424_3002 methyl-accepting chemotaxis sensory transducer; PFAM: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SMART: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SPTR: Methyl-accepting chemotaxis sensory transducer.
 
 
 0.983
AFZ36579.1
PFAM: Response regulator receiver domain; GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR003018:IPR000014:IPR001610:IPR 003661:IPR003594:IPR013655:IPR013656; KEGG: npu:Npun_R3572 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; PAS fold-3; GAF; Signal transduction response regulator, receiver domain; PAS fold-4; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor [...]
  
 
0.982
AFZ34616.1
PFAM: Methyl-accepting chemotaxis protein (MCP) signaling domain; COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089; KEGG: amr:AM1_5078 methyl-accepting chemotaxis signaling domain-containing protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: Methyl-accepting chemotaxis protein.
 
 
 0.979
AFZ34297.1
PFAM: Hpt domain; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterPro IPR008207; KEGG: cyh:Cyan8802_4111 putative CheA signal transduction histidine kinase; PFAM: Signal transduction histidine kinase, phosphotransfer (Hpt) domain; SMART: Signal transduction histidine kinase, phosphotransfer (Hpt) domain; SPTR: Putative CheA signal transduction histidine kinase.
 
   0.978
AFZ33754.1
PFAM: CheB methylesterase; COGs: COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain; InterPro IPR000673; KEGG: cyc:PCC7424_0432 CheB methylesterase; PFAM: Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase; PRIAM: Protein-glutamate methylesterase; SPTR: CheB methylesterase.
 
 
 0.975
Your Current Organism:
Stanieria cyanosphaera
NCBI taxonomy Id: 111780
Other names: Dermocarpa sp. PCC 7437, S. cyanosphaera PCC 7437, Stanieria cyanosphaera PCC 7437, Stanieria cyanosphaera str. PCC 7437, Stanieria sp. ATCC 29371, Stanieria sp. PCC 7437
Server load: low (14%) [HD]
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