STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ35050.1PFAM: Protein kinase domain; GAF domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; COGs: COG3899 ATPase; InterPro IPR000160:IPR017442:IPR003018:IPR002290; KEGG: npu:Npun_F3830 multi-sensor signal transduction multi-kinase; PFAM: Diguanylate cyclase, predicted; Serine/threonine-protein kinase-like domain; GAF; SMART: Diguanylate cyclase, predicted; Serine/threonine-protein kinase domain; GAF; SPTR: Multi-sensor signal transduction multi-kinase; TIGRFAM: Diguanylate cyclase, predicted. (1741 aa)    
Predicted Functional Partners:
AFZ37912.1
PFAM: Response regulator receiver domain; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: cyt:cce_2232 two-component sensor histidine kinase; PFAM: Signal transduction response regulator, receiver domain; PRIAM: Histidine kinase; SMART: Signal transduction response regulator, receiver domain; SPTR: Two-component sensor histidine kinase.
  
 0.921
AFZ34342.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain; GGDEF domain; PAS fold; FHA domain; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG2200 FOG: EAL domain; InterPro IPR000014:IPR000160:IPR000253:IPR001633; KEGG: cyt:cce_4177 hypothetical protein; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; Forkhead-associated; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; Forkhead-associated; PAS; SPTR: Putative uncharacterized protein; TIGRFAM: Diguanylate cyclase, predicted; PAS.
 
 
0.880
AFZ36465.1
PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR001789:IPR003661:IPR003594; KEGG: cyc:PCC7424_1421 response regulator receiver sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgr [...]
 
 
 0.878
AFZ36910.1
WD-40 repeat-containing protein; PFAM: WD domain, G-beta repeat; COGs: COG2319 FOG: WD40 repeat; InterPro IPR001680:IPR019781; KEGG: ana:alr2791 WD repeat-containing protein; PFAM: WD40 repeat, subgroup; SMART: WD40 repeat; SPTR: WD-40 repeat protein.
    0.873
AFZ37749.1
Multi-sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003018:IPR003594; KEGG: ana:all2956 two-component sensor histidine kinase; PFAM: ATPase-like, ATP-binding domain; GAF; SMART: ATPase-like, ATP-binding domain; GAF; SPTR: Two-component sensor histidine kinase.
   
 0.872
AFZ37354.1
PAS/PAC sensor hybrid histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR001789:IPR000014; KEGG: npu:Npun_R3591 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; Signal transduction [...]
 
 0.864
AFZ34098.1
PAS/PAC sensor hybrid histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003661:IPR003594:IPR001789:IPR013656:IPR 013655:IPR000014:IPR001610; KEGG: npu:Npun_F2908 multi-sensor hybrid histidine kinase; PFAM: Signal transduction response regulator, receiver domain; ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS [...]
 
 0.862
AFZ35266.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR001789:IPR000014:IPR001610:IPR003661:IPR 003594:IPR013767; KEGG: npu:Npun_R5611 multi-sensor hybrid histidine kinase; PFAM: Signal transduction response regulator, receiver domain; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; ATPase-like, ATP-binding domain [...]
 
 
 0.842
AFZ37782.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: cyt:cce_0164 two-component sensor histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: Two-component sensor histidine kinase.
 
 
 0.838
AFZ35541.1
PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003661:IPR003594:IPR 000014; KEGG: cyn:Cyan7425_3777 PAS/PAC sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; Signal t [...]
 
 0.827
Your Current Organism:
Stanieria cyanosphaera
NCBI taxonomy Id: 111780
Other names: Dermocarpa sp. PCC 7437, S. cyanosphaera PCC 7437, Stanieria cyanosphaera PCC 7437, Stanieria cyanosphaera str. PCC 7437, Stanieria sp. ATCC 29371, Stanieria sp. PCC 7437
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.