STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ35428.1PFAM: Bacterial regulatory proteins, luxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792; KEGG: amr:AM1_0029 LuxR family transcriptional regulator; PFAM: Transcription regulator LuxR, C-terminal; SMART: Transcription regulator LuxR, C-terminal; SPTR: Transcriptional regulator, LuxR family. (251 aa)    
Predicted Functional Partners:
AFZ34123.1
PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; COGs: COG4585 Signal transduction histidine kinase; InterPro IPR011712:IPR003594; KEGG: amr:AM1_0516 two-component sensor histidine kinase; PFAM: Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain; ATPase-like, ATP-binding domain; SMART: ATPase-like, ATP-binding domain; SPTR: Putative uncharacterized protein.
 
 
 0.686
AFZ35429.1
PFAM: MAPEG family; COGs: COG3788 Uncharacterized relative of glutathione S-transferase MAPEG superfamily; KEGG: cyh:Cyan8802_3208 uncharacterized relative of glutathione S-transferase MAPEG superfamily; SPTR: Uncharacterized relative of glutathione S-transferase MAPEG superfamily.
 
     0.656
AFZ36822.1
PFAM: Plasmid pRiA4b ORF-3-like protein; KEGG: cyn:Cyan7425_4772 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.610
AFZ34098.1
PAS/PAC sensor hybrid histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003661:IPR003594:IPR001789:IPR013656:IPR 013655:IPR000014:IPR001610; KEGG: npu:Npun_F2908 multi-sensor hybrid histidine kinase; PFAM: Signal transduction response regulator, receiver domain; ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS [...]
   
 
 0.594
AFZ35427.1
Protein of unknown function DUF6 transmembrane; PFAM: EamA-like transporter family; InterPro IPR000620; KEGG: cyc:PCC7424_4737 protein of unknown function DUF6 transmembrane; PFAM: Protein of unknown function DUF6, transmembrane; SPTR: Putative uncharacterized protein.
       0.578
AFZ35541.1
PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003661:IPR003594:IPR 000014; KEGG: cyn:Cyan7425_3777 PAS/PAC sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; Signal t [...]
   
 
 0.577
AFZ35431.1
Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase; COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002198; KEGG: amr:AM1_6146 oxidoreductase; PFAM: Short-chain dehydrogenase/reductase SDR; SPTR: Probable oxidoreductase.
 
     0.570
AFZ34462.1
PFAM: Bacterial regulatory proteins, luxR family; NB-ARC domain; InterPro IPR000792; KEGG: cyc:PCC7424_3256 transcriptional regulator, LuxR family; PFAM: Transcription regulator LuxR, C-terminal; SMART: Transcription regulator LuxR, C-terminal; SPTR: Transcriptional regulator, LuxR family.
 
 
 0.532
AFZ37007.1
PFAM: Bacterial regulatory proteins, tetR family; Phage integrase family; COGs: COG1309 Transcriptional regulator; InterPro IPR001647; KEGG: npu:Npun_R3984 TetR family transcriptional regulator; PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Transcriptional regulator, TetR family.
  
     0.515
AFZ35456.1
Hypothetical protein; PFAM: Glycosyl transferases group 1; KEGG: cyh:Cyan8802_3944 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.512
Your Current Organism:
Stanieria cyanosphaera
NCBI taxonomy Id: 111780
Other names: Dermocarpa sp. PCC 7437, S. cyanosphaera PCC 7437, Stanieria cyanosphaera PCC 7437, Stanieria cyanosphaera str. PCC 7437, Stanieria sp. ATCC 29371, Stanieria sp. PCC 7437
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.