STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
lipALipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (308 aa)    
Predicted Functional Partners:
lipB
Octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
 
 0.997
AFZ35117.1
PFAM: Biotin/lipoate A/B protein ligase family; COGs: COG0095 Lipoate-protein ligase A; InterPro IPR004143; KEGG: npu:Npun_F6359 biotin/lipoate A/B protein ligase; PFAM: Biotin/lipoate A/B protein ligase; SPTR: Biotin/lipoate A/B protein ligase.
 
 
 0.944
lipA-2
Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
  
  
 
0.905
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 
 0.795
AFZ35735.1
PFAM: Response regulator receiver domain; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: cyc:PCC7424_5208 response regulator receiver protein; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: Response regulator receiver protein.
       0.547
AFZ35734.1
KEGG: npu:Npun_R2291 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.514
AFZ34029.1
2-oxoglutarate dehydrogenase E2 component; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); Biotin-requiring enzyme; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR000089:IPR001078; KEGG: plu:plu2796 hypothetical protein; PFAM: 2-oxoacid dehydrogenase acyltransferase, catalytic domain; Biotin/lipoyl attachment; PRIAM: Dihydrolipoyllysine-residue acetyltransferase; SPTR: Similar to peptide synthetase. Putative transmembrane protein.
 
  
 0.486
AFZ35737.1
Pyridoxamine 5'-phosphate oxidase-related FMN-binding protein; PFAM: Pyridoxamine 5'-phosphate oxidase; InterPro IPR011576; KEGG: cyp:PCC8801_3068 pyridoxamine 5'-phosphate oxidase-related FMN-binding; PFAM: Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain; SPTR: Pyridoxamine 5'-phosphate oxidase-related FMN-binding.
       0.485
AFZ35738.1
Glycogen debranching enzyme; PFAM: Amylo-alpha-1,6-glucosidase; Glycogen debranching enzyme N terminal; TIGRFAM: glycogen debranching enzyme, archaeal type, putative; COGs: COG3408 Glycogen debranching protein; InterPro IPR006451:IPR010401; KEGG: npu:Npun_F1435 glycogen debranching enzyme, putative; PFAM: Amylo-alpha-1,6-glucosidase; SPTR: Glycogen debranching enzyme, putative; TIGRFAM: Glycogen debranching enzyme, archaeal type.
       0.475
gcvP
Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
  
 0.442
Your Current Organism:
Stanieria cyanosphaera
NCBI taxonomy Id: 111780
Other names: Dermocarpa sp. PCC 7437, S. cyanosphaera PCC 7437, Stanieria cyanosphaera PCC 7437, Stanieria cyanosphaera str. PCC 7437, Stanieria sp. ATCC 29371, Stanieria sp. PCC 7437
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