STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
AFZ36018.1Enoyl-(acyl-carrier-protein) reductase (NADH); PFAM: short chain dehydrogenase; COGs: COG0623 Enoyl-(acyl-carrier-protein); InterPro IPR002198; KEGG: cyc:PCC7424_0373 enoyl-(acyl carrier protein) reductase; PFAM: Short-chain dehydrogenase/reductase SDR; PRIAM: Enoyl-[acyl-carrier-protein] reductase (NADH); SPTR: Short-chain dehydrogenase/reductase SDR. (259 aa)    
Predicted Functional Partners:
AFZ34885.1
PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterPro IPR004410:IPR014043; KEGG: cyc:PCC7424_1044 malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; PRIAM: [Acyl-carrier-protein] S-malonyltransferase; SPTR: Malonyl CoA-acyl carrier protein transacylase; TIGRFAM: Malonyl CoA-acyl carrier protein transacylase.
 
 
 0.988
AFZ34501.1
3-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 
 0.986
AFZ34746.1
PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; COGs: COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; InterPro IPR014030:IPR014031; KEGG: cyc:PCC7424_0582 3-oxoacyl-(acyl carrier protein) synthase II; PFAM: Beta-ketoacyl synthase, C-terminal; Beta-ketoacyl synthase, N-terminal; PRIAM: Beta-ketoacyl-acyl-carrier-protein synthase I; SPTR: Beta-ketoacyl synthase, C-terminal domain protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 
 0.986
fabZ
3-hydroxyacyl-(acyl-carrier-protein) dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
 
 
 0.974
AFZ35731.1
3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
0.923
AFZ35156.1
3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: short chain dehydrogenase; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198; KEGG: mpo:Mpop_4560 short-chain dehydrogenase/reductase SDR; PFAM: Short-chain dehydrogenase/reductase SDR; PRIAM: 3-oxoacyl-[acyl-carrier-protein] reductase; SPTR: Putative ketoacyl reductase.
  
 
 0.911
AFZ35459.1
PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; COGs: COG3321 Polyketide synthase modules and related protein; InterPro IPR014030:IPR014031; KEGG: cyt:cce_3079 polyketide synthase; PFAM: Beta-ketoacyl synthase, N-terminal; Beta-ketoacyl synthase, C-terminal; PRIAM: 6-deoxyerythronolide-B synthase; SPTR: CrpB; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
   
 0.905
AFZ36190.1
Oleoyl-(acyl-carrier-protein) hydrolase; PFAM: Thioesterase domain; COGs: COG3208 thioesterase involved in non-ribosomal peptide biosynthesis; InterPro IPR001031; KEGG: npu:Npun_R3419 thioesterase; PFAM: Thioesterase; PRIAM: Oleoyl-[acyl-carrier-protein] hydrolase; SPTR: Thioesterase.
     
 0.901
AFZ34889.1
Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase; COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002198; KEGG: ava:Ava_2965 short-chain dehydrogenase/reductase SDR; PFAM: Short-chain dehydrogenase/reductase SDR; SPTR: Oxidoreductase, short chain dehydrogenase/reductase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
  0.900
lipB
Octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
     
  0.800
Your Current Organism:
Stanieria cyanosphaera
NCBI taxonomy Id: 111780
Other names: Dermocarpa sp. PCC 7437, S. cyanosphaera PCC 7437, Stanieria cyanosphaera PCC 7437, Stanieria cyanosphaera str. PCC 7437, Stanieria sp. ATCC 29371, Stanieria sp. PCC 7437
Server load: low (10%) [HD]
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