STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ36764.1Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase; COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002198; KEGG: cyc:PCC7424_0301 short-chain dehydrogenase/reductase SDR; PFAM: Short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (307 aa)    
Predicted Functional Partners:
AFZ36193.1
Thioester reductase domain protein; PFAM: Male sterility protein; Phosphopantetheine attachment site; AMP-binding enzyme; Condensation domain; TIGRFAM: thioester reductase domain; COGs: COG1020 Non-ribosomal peptide synthetase modules and related protein; InterProIPR001242:IPR000873:IPR006163:IPR013120:IPR 010071:IPR010080; KEGG: npu:Npun_R3433 amino acid adenylation domain-containing protein; PFAM: AMP-dependent synthetase/ligase; Condensation domain; Phosphopantetheine-binding; Male sterility, NAD-binding; PRIAM: Phenylalanine racemase (ATP-hydrolyzing)., Sterol-4-alpha-carboxylate 3 [...]
 
  
 0.898
AFZ36195.1
Amino acid adenylation domain protein; PFAM: Phosphopantetheine attachment site; AMP-binding enzyme; Condensation domain; TIGRFAM: amino acid adenylation domain; COGs: COG1020 Non-ribosomal peptide synthetase modules and related protein; InterPro IPR001242:IPR000873:IPR006163:IPR010071; KEGG: amr:AM1_A0235 peptide synthetase, putative; PFAM: AMP-dependent synthetase/ligase; Condensation domain; Phosphopantetheine-binding; PRIAM: Phenylalanine racemase (ATP-hydrolyzing); SPTR: Peptide synthetase, putative; TIGRFAM: Amino acid adenylation.
 
  
 0.891
AFZ37662.1
Amino acid adenylation domain protein; PFAM: Male sterility protein; Phosphopantetheine attachment site; Methyltransferase domain; AMP-binding enzyme; TIGRFAM: amino acid adenylation domain; thioester reductase domain; COGs: COG1020 Non-ribosomal peptide synthetase modules and related protein; InterProIPR010071:IPR010080:IPR000873:IPR013217:IPR 006163:IPR013120; KEGG: mar:MAE_60010 McnC protein; PFAM: AMP-dependent synthetase/ligase; Methyltransferase type 12; Phosphopantetheine-binding; Male sterility, NAD-binding; PRIAM: Phenylalanine racemase (ATP-hydrolyzing); SPTR: Amino acid aden [...]
   
 0.609
AFZ34701.1
PFAM: Acyl transferase domain; Beta-ketoacyl synthase, C-terminal domain; Phosphopantetheine attachment site; KR domain; Alcohol dehydrogenase GroES-like domain; Beta-ketoacyl synthase, N-terminal domain; Aminotransferase class I and II; Zinc-binding dehydrogenase; TIGRFAM: 8-amino-7-oxononanoate synthase; malonyl CoA-acyl carrier protein transacylase; COGs: COG3321 Polyketide synthase modules and related protein; InterProIPR014030:IPR014031:IPR014043:IPR013154:IPR 013149:IPR013968:IPR006163:IPR004839; KEGG: npu:Npun_F3360 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase, N-termina [...]
 
 
 0.575
AFZ33823.1
Phenylalanine racemase (ATP-hydrolyzing), Mycocerosate synthase; PFAM: Acyl transferase domain; AMP-binding enzyme; Beta-ketoacyl synthase, C-terminal domain; Phosphopantetheine attachment site; KR domain; Alcohol dehydrogenase GroES-like domain; Beta-ketoacyl synthase, N-terminal domain; Zinc-binding dehydrogenase; COGs: COG3321 Polyketide synthase modules and related protein; InterProIPR000873:IPR006163:IPR014030:IPR014031:IPR 014043:IPR013154:IPR013149:IPR013968; KEGG: npu:Npun_F3360 beta-ketoacyl synthase; PFAM: Polyketide synthase, KR; Beta-ketoacyl synthase, N-terminal; Phosphopa [...]
 
 
 
 0.517
AFZ37598.1
Long-chain-fatty-acid--CoA ligase, 6-deoxyerythronolide-B synthase; PFAM: Phosphopantetheine attachment site; Acyl transferase domain; KR domain; Beta-ketoacyl synthase, N-terminal domain; Sulfotransferase domain; AMP-binding enzyme; Beta-ketoacyl synthase, C-terminal domain; COGs: COG3321 Polyketide synthase modules and related protein; InterProIPR000873:IPR006163:IPR014030:IPR014031:IPR 014043:IPR013968:IPR000863:IPR000073; KEGG: cyc:PCC7424_1874 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase, N-terminal; AMP-dependent synthetase/ligase; Phosphopantetheine-binding; Beta-ketoacy [...]
  
 
 0.481
Your Current Organism:
Stanieria cyanosphaera
NCBI taxonomy Id: 111780
Other names: Dermocarpa sp. PCC 7437, S. cyanosphaera PCC 7437, Stanieria cyanosphaera PCC 7437, Stanieria cyanosphaera str. PCC 7437, Stanieria sp. ATCC 29371, Stanieria sp. PCC 7437
Server load: low (14%) [HD]
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