STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ36949.1InterPro IPR013027; KEGG: cyp:PCC8801_3664 hypothetical protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Putative uncharacterized protein. (584 aa)    
Predicted Functional Partners:
AFZ34982.1
PFAM: 2Fe-2S iron-sulfur cluster binding domain; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; COGs: COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterPro IPR004489; KEGG: cag:Cagg_1578 succinate dehydrogenase/fumarate reductase iron-sulfur subunit; SPTR: Succinate dehydrogenase and fumarate reductase iron-sulfur protein; TIGRFAM: Succinate dehydrogenase/fumarate reductase iron-sulphur protein.
  
 0.977
AFZ34152.1
PFAM: Sigma-54 interaction domain; Cyclic nucleotide-binding domain; COGs: COG1221 Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain; InterPro IPR000595:IPR002078; KEGG: cyc:PCC7424_3607 cyclic nucleotide-binding protein; PFAM: Cyclic nucleotide-binding; RNA polymerase sigma factor 54, interaction; SMART: Cyclic nucleotide-binding; SPTR: Cyclic nucleotide-binding protein.
  
 
 0.757
ndhH
NAD(P)H-quinone oxidoreductase subunit H; NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
   
 
 0.753
gcvP
Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
  
 0.748
petC
Cytochrome b6-f complex iron-sulfur subunit; Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
  
 
 0.747
AFZ34846.1
PFAM: Citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; COGs: COG0372 Citrate synthase; InterPro IPR011278:IPR002020; KEGG: cyh:Cyan8802_1408 citrate synthase; PFAM: Citrate synthase-like; PRIAM: Citrate (Si)-synthase; SPTR: 2-methylcitrate synthase/citrate synthase II; TIGRFAM: 2-methylcitrate synthase/citrate synthase type I; Belongs to the citrate synthase family.
  
 
 0.717
AFZ37433.1
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; COGs: COG0281 Malic enzyme; InterPro IPR002912:IPR012301:IPR012302; KEGG: cyc:PCC7424_1195 malate dehydrogenase (oxaloacetate-decarboxylating); PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Amino acid-binding ACT; PRIAM: Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); SPTR: Malate dehydrogenase (Oxaloacetate-decarboxylating).
  
  
 0.707
AFZ36526.1
Succinate--CoA ligase (ADP-forming); PFAM: ATP-grasp domain; TIGRFAM: succinyl-CoA synthetase, beta subunit; COGs: COG0045 Succinyl-CoA synthetase beta subunit; InterPro IPR013650; KEGG: cyc:PCC7424_0300 ATP-grasp domain protein; PFAM: ATP-grasp fold, succinyl-CoA synthetase-type; PRIAM: Succinate--CoA ligase (ADP-forming); SPTR: ATP-grasp domain protein.
  
 
 0.704
AFZ36527.1
Succinate--CoA ligase (ADP-forming); PFAM: CoA binding domain; TIGRFAM: succinyl-CoA synthetase, alpha subunit; COGs: COG0074 Succinyl-CoA synthetase alpha subunit; InterPro IPR003781:IPR005811; KEGG: cyc:PCC7424_0299 CoA-binding domain protein; PFAM: CoA-binding; ATP-citrate lyase/succinyl-CoA ligase; PRIAM: Succinate--CoA ligase (ADP-forming); SPTR: CoA-binding domain protein.
  
 
 0.703
atpA
ATP synthase F1 subcomplex alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.
   
  
 0.638
Your Current Organism:
Stanieria cyanosphaera
NCBI taxonomy Id: 111780
Other names: Dermocarpa sp. PCC 7437, S. cyanosphaera PCC 7437, Stanieria cyanosphaera PCC 7437, Stanieria cyanosphaera str. PCC 7437, Stanieria sp. ATCC 29371, Stanieria sp. PCC 7437
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