STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ37442.1PFAM: Acyl-CoA dehydrogenase, N-terminal domain; COGs: COG1960 Acyl-CoA dehydrogenase; InterPro IPR006092; KEGG: cyh:Cyan8802_3114 acyl-CoA dehydrogenase domain protein; PFAM: Acyl-CoA dehydrogenase, N-terminal; SPTR: Acyl-CoA dehydrogenase domain protein. (365 aa)    
Predicted Functional Partners:
AFZ37598.1
Long-chain-fatty-acid--CoA ligase, 6-deoxyerythronolide-B synthase; PFAM: Phosphopantetheine attachment site; Acyl transferase domain; KR domain; Beta-ketoacyl synthase, N-terminal domain; Sulfotransferase domain; AMP-binding enzyme; Beta-ketoacyl synthase, C-terminal domain; COGs: COG3321 Polyketide synthase modules and related protein; InterProIPR000873:IPR006163:IPR014030:IPR014031:IPR 014043:IPR013968:IPR000863:IPR000073; KEGG: cyc:PCC7424_1874 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase, N-terminal; AMP-dependent synthetase/ligase; Phosphopantetheine-binding; Beta-ketoacy [...]
  
 0.887
AFZ37732.1
acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR002155:IPR020616:IPR020617; KEGG: cyn:Cyan7425_4054 acetyl-CoA acetyltransferase; PFAM: Thiolase, N-terminal; Thiolase, C-terminal; PRIAM: Acetyl-CoA C-acetyltransferase; SPTR: Acetyl-CoA acetyltransferase; TIGRFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.764
gcvP
Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
  
 0.716
AFZ36973.1
Long-chain-fatty-acid--CoA ligase; PFAM: AMP-binding enzyme; COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR000873; KEGG: cyt:cce_1133 long-chain-fatty-acid CoA ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Long-chain-fatty-acid--CoA ligase; SPTR: Long-chain-fatty-acid CoA ligase.
  
 0.693
AFZ35012.1
COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); KEGG: cyh:Cyan8802_3054 alpha/beta hydrolase fold protein; SPTR: Alpha/beta hydrolase fold protein.
  
   0.688
AFZ34701.1
PFAM: Acyl transferase domain; Beta-ketoacyl synthase, C-terminal domain; Phosphopantetheine attachment site; KR domain; Alcohol dehydrogenase GroES-like domain; Beta-ketoacyl synthase, N-terminal domain; Aminotransferase class I and II; Zinc-binding dehydrogenase; TIGRFAM: 8-amino-7-oxononanoate synthase; malonyl CoA-acyl carrier protein transacylase; COGs: COG3321 Polyketide synthase modules and related protein; InterProIPR014030:IPR014031:IPR014043:IPR013154:IPR 013149:IPR013968:IPR006163:IPR004839; KEGG: npu:Npun_F3360 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase, N-termina [...]
  
 0.596
AFZ33823.1
Phenylalanine racemase (ATP-hydrolyzing), Mycocerosate synthase; PFAM: Acyl transferase domain; AMP-binding enzyme; Beta-ketoacyl synthase, C-terminal domain; Phosphopantetheine attachment site; KR domain; Alcohol dehydrogenase GroES-like domain; Beta-ketoacyl synthase, N-terminal domain; Zinc-binding dehydrogenase; COGs: COG3321 Polyketide synthase modules and related protein; InterProIPR000873:IPR006163:IPR014030:IPR014031:IPR 014043:IPR013154:IPR013149:IPR013968; KEGG: npu:Npun_F3360 beta-ketoacyl synthase; PFAM: Polyketide synthase, KR; Beta-ketoacyl synthase, N-terminal; Phosphopa [...]
  
 0.586
AFZ36826.1
Alcohol dehydrogenase AdhE; PFAM: Aldehyde dehydrogenase family; Iron-containing alcohol dehydrogenase; COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR001670; KEGG: cyc:PCC7424_3674 bifunctional acetaldehyde-CoA/alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, iron-type; PRIAM: Acetaldehyde dehydrogenase (acetylating); SPTR: Alcohol dehydrogenase, iron-containing family; acetaldehyde dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
  
 0.548
AFZ33838.1
Long-chain-fatty-acid--CoA ligase; PFAM: AMP-binding enzyme; COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: npu:Npun_R2067 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Long-chain-fatty-acid--CoA ligase; SPTR: AMP-dependent synthetase and ligase.
  
 
 0.544
AFZ36341.1
PFAM: Bacterial protein of unknown function (DUF839); COGs: COG3211 phosphatase; InterPro IPR008557; KEGG: cyc:PCC7424_4941 protein of unknown function DUF839; PFAM: Protein of unknown function DUF839, bacterial; SPTR: Putative uncharacterized protein.
  
     0.522
Your Current Organism:
Stanieria cyanosphaera
NCBI taxonomy Id: 111780
Other names: Dermocarpa sp. PCC 7437, S. cyanosphaera PCC 7437, Stanieria cyanosphaera PCC 7437, Stanieria cyanosphaera str. PCC 7437, Stanieria sp. ATCC 29371, Stanieria sp. PCC 7437
Server load: low (10%) [HD]