STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ37702.1KEGG: cyn:Cyan7425_2210 hypothetical protein; SPTR: Putative uncharacterized protein. (343 aa)    
Predicted Functional Partners:
AFZ37701.1
rRNA (guanine-N(2)-)-methyltransferase; PFAM: Putative RNA methylase family UPF0020; THUMP domain; COGs: COG0116 N6-adenine-specific DNA methylase; InterPro IPR004114:IPR000241; KEGG: cyh:Cyan8802_1292 putative RNA methylase; PFAM: Putative RNA methylase; THUMP; PRIAM: rRNA (guanine-N(2)-)-methyltransferase; SPTR: Putative RNA methylase; Belongs to the methyltransferase superfamily.
       0.620
AFZ34701.1
PFAM: Acyl transferase domain; Beta-ketoacyl synthase, C-terminal domain; Phosphopantetheine attachment site; KR domain; Alcohol dehydrogenase GroES-like domain; Beta-ketoacyl synthase, N-terminal domain; Aminotransferase class I and II; Zinc-binding dehydrogenase; TIGRFAM: 8-amino-7-oxononanoate synthase; malonyl CoA-acyl carrier protein transacylase; COGs: COG3321 Polyketide synthase modules and related protein; InterProIPR014030:IPR014031:IPR014043:IPR013154:IPR 013149:IPR013968:IPR006163:IPR004839; KEGG: npu:Npun_F3360 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase, N-termina [...]
  
 
 0.588
nnrE
YjeF-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...]
  
    0.585
AFZ37598.1
Long-chain-fatty-acid--CoA ligase, 6-deoxyerythronolide-B synthase; PFAM: Phosphopantetheine attachment site; Acyl transferase domain; KR domain; Beta-ketoacyl synthase, N-terminal domain; Sulfotransferase domain; AMP-binding enzyme; Beta-ketoacyl synthase, C-terminal domain; COGs: COG3321 Polyketide synthase modules and related protein; InterProIPR000873:IPR006163:IPR014030:IPR014031:IPR 014043:IPR013968:IPR000863:IPR000073; KEGG: cyc:PCC7424_1874 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase, N-terminal; AMP-dependent synthetase/ligase; Phosphopantetheine-binding; Beta-ketoacy [...]
  
 
 0.572
AFZ37533.1
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
 
  
 0.570
AFZ36285.1
KEGG: ana:all5244 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.561
AFZ33823.1
Phenylalanine racemase (ATP-hydrolyzing), Mycocerosate synthase; PFAM: Acyl transferase domain; AMP-binding enzyme; Beta-ketoacyl synthase, C-terminal domain; Phosphopantetheine attachment site; KR domain; Alcohol dehydrogenase GroES-like domain; Beta-ketoacyl synthase, N-terminal domain; Zinc-binding dehydrogenase; COGs: COG3321 Polyketide synthase modules and related protein; InterProIPR000873:IPR006163:IPR014030:IPR014031:IPR 014043:IPR013154:IPR013149:IPR013968; KEGG: npu:Npun_F3360 beta-ketoacyl synthase; PFAM: Polyketide synthase, KR; Beta-ketoacyl synthase, N-terminal; Phosphopa [...]
  
 
 0.506
nadE
NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.501
AFZ35748.1
KEGG: cyh:Cyan8802_2002 hypothetical protein; SPTR: Putative uncharacterized protein.
 
  
 0.493
AFZ35079.1
Protein of unknown function DUF2330; PFAM: Uncharacterized protein conserved in bacteria (DUF2330); COGs: COG4402 conserved hypothetical protein; InterPro IPR019283; KEGG: cyc:PCC7424_4567 hypothetical protein; PFAM: Protein of unknown function DUF2330; SPTR: Putative uncharacterized protein.
  
     0.490
Your Current Organism:
Stanieria cyanosphaera
NCBI taxonomy Id: 111780
Other names: Dermocarpa sp. PCC 7437, S. cyanosphaera PCC 7437, Stanieria cyanosphaera PCC 7437, Stanieria cyanosphaera str. PCC 7437, Stanieria sp. ATCC 29371, Stanieria sp. PCC 7437
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.