STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Cooccurrence
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Experiments
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[Homology]
Score
AFZ37749.1Multi-sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003018:IPR003594; KEGG: ana:all2956 two-component sensor histidine kinase; PFAM: ATPase-like, ATP-binding domain; GAF; SMART: ATPase-like, ATP-binding domain; GAF; SPTR: Two-component sensor histidine kinase. (661 aa)    
Predicted Functional Partners:
AFZ34098.1
PAS/PAC sensor hybrid histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003661:IPR003594:IPR001789:IPR013656:IPR 013655:IPR000014:IPR001610; KEGG: npu:Npun_F2908 multi-sensor hybrid histidine kinase; PFAM: Signal transduction response regulator, receiver domain; ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS [...]
  
 
0.957
AFZ37748.1
PFAM: Response regulator receiver domain; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: ana:all2955 two-component response regulator; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: Two-component response regulator.
 
 0.952
AFZ35050.1
PFAM: Protein kinase domain; GAF domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; COGs: COG3899 ATPase; InterPro IPR000160:IPR017442:IPR003018:IPR002290; KEGG: npu:Npun_F3830 multi-sensor signal transduction multi-kinase; PFAM: Diguanylate cyclase, predicted; Serine/threonine-protein kinase-like domain; GAF; SMART: Diguanylate cyclase, predicted; Serine/threonine-protein kinase domain; GAF; SPTR: Multi-sensor signal transduction multi-kinase; TIGRFAM: Diguanylate cyclase, predicted.
   
 0.872
AFZ35265.1
ATP-binding region ATPase domain protein; PFAM: Protein kinase domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; His Kinase A (phosphoacceptor) domain; COGs: COG3899 ATPase; InterProIPR020635:IPR002290:IPR003018:IPR003661:IPR 003594:IPR001789:IPR017442; KEGG: cyn:Cyan7425_0791 ATP-binding region ATPase domain protein; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Serine/threonine-protein kinase-like domain; GAF; Signal transduction response regu [...]
 
0.817
AFZ35526.1
PFAM: Response regulator receiver domain; COGs: COG0784 FOG: CheY-like receiver; InterPro IPR001789; KEGG: ana:all2955 two-component response regulator; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: Two-component response regulator.
 
 0.809
AFZ37747.1
Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain; Response regulator receiver domain; GGDEF domain; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterPro IPR001789:IPR000160:IPR001633:IPR000014; KEGG: naz:Aazo_0695 diguanylate cyclase/phosphodiesterase; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; Signal transduction response regulator, receiver domain; SMART: Diguanylat [...]
  
 
 0.795
AFZ35541.1
PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003661:IPR003594:IPR 000014; KEGG: cyn:Cyan7425_3777 PAS/PAC sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; Signal t [...]
 
 
0.759
AFZ33971.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR003018:IPR013655:IPR013656:IPR 003661:IPR003594:IPR000014:IPR001610; KEGG: npu:Npun_R3572 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction response regulator, receiver domain; GAF; PAS fold-3; PAS fold-4; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor [...]
  
 
0.753
AFZ35908.1
Putative GAF sensor protein; PFAM: GAF domain; COGs: COG2203 FOG: GAF domain; InterPro IPR003018; KEGG: ava:Ava_3204 sensor protein; PFAM: GAF; SMART: GAF; SPTR: Possible Sensor with GAF domain.
 
    
0.718
AFZ35266.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR001789:IPR000014:IPR001610:IPR003661:IPR 003594:IPR013767; KEGG: npu:Npun_R5611 multi-sensor hybrid histidine kinase; PFAM: Signal transduction response regulator, receiver domain; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; ATPase-like, ATP-binding domain [...]
  
 
0.712
Your Current Organism:
Stanieria cyanosphaera
NCBI taxonomy Id: 111780
Other names: Dermocarpa sp. PCC 7437, S. cyanosphaera PCC 7437, Stanieria cyanosphaera PCC 7437, Stanieria cyanosphaera str. PCC 7437, Stanieria sp. ATCC 29371, Stanieria sp. PCC 7437
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