Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AFY36637.1Pirin domain protein; PFAM: Pirin; COGs: COG1741 Pirin-related protein; InterPro IPR003829; KEGG: syn:sll1773 hypothetical protein; PFAM: Pirin, N-terminal; SPTR: Pirin-like protein sll1773; Belongs to the pirin family. (233 aa)    
Predicted Functional Partners:
AFY39300.1
PFAM: Catalytic LigB subunit of aromatic ring-opening dioxygenase; COGs: COG3384 conserved hypothetical protein; InterPro IPR004183; KEGG: bbt:BBta_6127 putative extradiol ring-cleavage dioxygenase; PFAM: Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B; SPTR: Extradiol-type ring-opening dioxygenase.
 
  
 0.666
AFY36636.1
PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain; COGs: COG0583 Transcriptional regulator; InterPro IPR000847:IPR005119; KEGG: syn:slr1871 transcriptional regulator; PFAM: LysR, substrate-binding; HTH transcriptional regulator, LysR; SPTR: Transcriptional regulator.
     
 0.614
AFY36638.1
Iron sulfur domain-containing, CDGSH-type; PFAM: Iron-binding zinc finger CDGSH type; InterPro IPR006622:IPR018967; KEGG: cyc:PCC7424_1481 zinc finger CDGSH-type domain protein; PFAM: Iron sulphur-containing domain, CDGSH-type; SPTR: Zinc finger CDGSH-type domain protein.
       0.526
AFY38510.1
PFAM: Glutathione S-transferase, C-terminal domain; COGs: COG0435 glutathione S-transferase; InterPro IPR004046; KEGG: syp:SYNPCC7002_A2413 hypothetical protein; PFAM: Glutathione S-transferase, C-terminal; PRIAM: Glutathione transferase; SPTR: Putative uncharacterized protein.
     
 0.421
AFY36825.1
PFAM: HxlR-like helix-turn-helix; COGs: COG1733 transcriptional regulator protein; InterPro IPR002577; KEGG: bph:Bphy_6381 HxlR family transcriptional regulator; PFAM: Helix-turn-helix, HxlR type; SPTR: Transcriptional regulator, HxlR family.
     
 0.411
Your Current Organism:
Leptolyngbya sp. PCC7376
NCBI taxonomy Id: 111781
Other names: Enugrolinea bermudensis PCC 7376, L. sp. PCC 7376, Leptolyngbya PCC7376, Leptolyngbya sp. PCC 7376
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