Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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co-expression
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AFY36681.1PFAM: Response regulator receiver domain; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: syp:SYNPCC7002_A1576 response regulator receiver domain-containing protein; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: Response regulator receiver domain protein. (184 aa)    
Predicted Functional Partners:
AFY38695.1
PFAM: Response regulator receiver domain; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: syp:SYNPCC7002_A0046 two-component response regulator; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: Two-component response regulator.
  
   0.772
AFY37766.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003018:IPR003594; KEGG: syp:SYNPCC7002_A1954 putative two-component sensor histidine kinase; PFAM: ATPase-like, ATP-binding domain; SMART: ATPase-like, ATP-binding domain; GAF; SPTR: Putative two-component sensor histidine kinase.
  
 
   0.750
AFY38892.1
Integral membrane sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: syp:SYNPCC7002_A1363 two-component sensor histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: Two-component sensor [...]
  
 
   0.748
sasA
Histidine kinase; May be involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs.
  
 
   0.746
AFY37536.1
Multi-sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterProIPR001789:IPR000014:IPR003661:IPR003594:IPR 013767; KEGG: gvi:gll0634 two-component hybrid sensor and regulator; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; PAS f [...]
 
 
 0.738
AFY36749.1
PAS/PAC sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterProIPR001610:IPR003661:IPR003594:IPR000014:IPR 013655; KEGG: syp:SYNPCC7002_A2365 two-component hybrid sensor kinase/response regulator; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-3; SMART: ATPase-like, ATP-binding domain; Signal transduction his [...]
 
 
 
 0.734
AFY40233.1
Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: syp:SYNPCC7002_A0496 two-component response regulator; transcriptional regulatory protein; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; SPTR: Two-component [...]
  
   0.721
AFY37361.1
Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: syp:SYNPCC7002_A0937 two-component response regulator; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; SPTR: Two-component response regulator.
  
   0.712
AFY36835.1
Integral membrane sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: npu:Npun_R3054 CHASE sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: Chase sensor s [...]
  
 
   0.708
AFY37735.1
Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: syp:SYNPCC7002_A0851 two-component response regulator, OmpR subfamily protein; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; SPTR: Probable transcriptional [...]
  
   0.707
Your Current Organism:
Leptolyngbya sp. PCC7376
NCBI taxonomy Id: 111781
Other names: Enugrolinea bermudensis PCC 7376, L. sp. PCC 7376, Leptolyngbya PCC7376, Leptolyngbya sp. PCC 7376
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