| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AFY36700.1 | ureG | Lepto7376_0256 | Lepto7376_0262 | Urea ABC transporter membrane protein; PFAM: Branched-chain amino acid transport system / permease component; TIGRFAM: urea ABC transporter, permease protein UrtB; COGs: COG0559 Branched-chain amino acid ABC-type transport system permease components; InterPro IPR017779:IPR001851; KEGG: mar:MAE_06210 UreA transport system permease protein; PFAM: Bacterial inner-membrane translocator; SPTR: Urea transport system permease protein; TIGRFAM: ABC transporter, urea, permease protein, UrtB. | Urease accessory protein ureG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. | 0.401 |
| AFY36704.1 | AFY40251.1 | Lepto7376_0260 | Lepto7376_4122 | Hypothetical protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. | Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR004392:IPR003495; KEGG: syp:SYNPCC7002_A1747 hydrogenase accessory protein HypB; PFAM: Cobalamin (vitamin B12) biosynthesis CobW-like; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: Hydrogenase accessory protein HypB. | 0.449 |
| AFY36704.1 | ureA | Lepto7376_0260 | Lepto7376_0264 | Hypothetical protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. | PFAM: Urease, gamma subunit; TIGRFAM: urease, gamma subunit; COGs: COG0831 Urea amidohydrolase (urease) gamma subunit; HAMAP: Urease, gamma subunit; InterPro IPR002026:IPR012010; KEGG: ter:Tery_0746 urease, gamma subunit; PFAM: Urease, alpha/gamma subunit; PRIAM: Urease; SPTR: Urease subunit gamma; TIGRFAM: Urease, alpha/gamma subunit; Belongs to the urease gamma subunit family. | 0.699 |
| AFY36704.1 | ureB | Lepto7376_0260 | Lepto7376_0263 | Hypothetical protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. | PFAM: Urease beta subunit; TIGRFAM: urease, beta subunit; COGs: COG0832 Urea amidohydrolase (urease) beta subunit; HAMAP: Urease, beta subunit; InterPro IPR002019; KEGG: ter:Tery_0747 urease subunit beta; PFAM: Urease, beta subunit; PRIAM: Urease; SPTR: Urease subunit beta; TIGRFAM: Urease, beta subunit; Belongs to the urease beta subunit family. | 0.716 |
| AFY36704.1 | ureC | Lepto7376_0260 | Lepto7376_0258 | Hypothetical protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. | PFAM: Urease alpha-subunit, N-terminal domain; Amidohydrolase family; TIGRFAM: urease, alpha subunit; COGs: COG0804 Urea amidohydrolase (urease) alpha subunit; HAMAP: Urease, alpha subunit; InterPro IPR005848:IPR011612:IPR006680; KEGG: ter:Tery_0752 urease subunit alpha; PFAM: Amidohydrolase 1; Urease alpha-subunit, N-terminal; PRIAM: Urease; SPTR: Urease subunit alpha; TIGRFAM: Urease, alpha subunit. | 0.795 |
| AFY36704.1 | ureD | Lepto7376_0260 | Lepto7376_0261 | Hypothetical protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. | Urease accessory protein ureD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.932 |
| AFY36704.1 | ureF | Lepto7376_0260 | Lepto7376_0259 | Hypothetical protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. | Urease accessory protein ureF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.961 |
| AFY36704.1 | ureG | Lepto7376_0260 | Lepto7376_0262 | Hypothetical protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. | Urease accessory protein ureG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. | 0.810 |
| AFY40251.1 | AFY36704.1 | Lepto7376_4122 | Lepto7376_0260 | Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR004392:IPR003495; KEGG: syp:SYNPCC7002_A1747 hydrogenase accessory protein HypB; PFAM: Cobalamin (vitamin B12) biosynthesis CobW-like; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: Hydrogenase accessory protein HypB. | Hypothetical protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. | 0.449 |
| AFY40251.1 | hypA | Lepto7376_4122 | Lepto7376_4123 | Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR004392:IPR003495; KEGG: syp:SYNPCC7002_A1747 hydrogenase accessory protein HypB; PFAM: Cobalamin (vitamin B12) biosynthesis CobW-like; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: Hydrogenase accessory protein HypB. | Hydrogenase nickel incorporation protein hypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.993 |
| AFY40251.1 | ureD | Lepto7376_4122 | Lepto7376_0261 | Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR004392:IPR003495; KEGG: syp:SYNPCC7002_A1747 hydrogenase accessory protein HypB; PFAM: Cobalamin (vitamin B12) biosynthesis CobW-like; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: Hydrogenase accessory protein HypB. | Urease accessory protein ureD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.575 |
| AFY40251.1 | ureF | Lepto7376_4122 | Lepto7376_0259 | Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR004392:IPR003495; KEGG: syp:SYNPCC7002_A1747 hydrogenase accessory protein HypB; PFAM: Cobalamin (vitamin B12) biosynthesis CobW-like; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: Hydrogenase accessory protein HypB. | Urease accessory protein ureF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.688 |
| AFY40251.1 | ureG | Lepto7376_4122 | Lepto7376_0262 | Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR004392:IPR003495; KEGG: syp:SYNPCC7002_A1747 hydrogenase accessory protein HypB; PFAM: Cobalamin (vitamin B12) biosynthesis CobW-like; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: Hydrogenase accessory protein HypB. | Urease accessory protein ureG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. | 0.559 |
| hypA | AFY40251.1 | Lepto7376_4123 | Lepto7376_4122 | Hydrogenase nickel incorporation protein hypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR004392:IPR003495; KEGG: syp:SYNPCC7002_A1747 hydrogenase accessory protein HypB; PFAM: Cobalamin (vitamin B12) biosynthesis CobW-like; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: Hydrogenase accessory protein HypB. | 0.993 |
| hypA | ureD | Lepto7376_4123 | Lepto7376_0261 | Hydrogenase nickel incorporation protein hypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | Urease accessory protein ureD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.714 |
| hypA | ureF | Lepto7376_4123 | Lepto7376_0259 | Hydrogenase nickel incorporation protein hypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | Urease accessory protein ureF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.724 |
| hypA | ureG | Lepto7376_4123 | Lepto7376_0262 | Hydrogenase nickel incorporation protein hypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | Urease accessory protein ureG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. | 0.960 |
| ureA | AFY36704.1 | Lepto7376_0264 | Lepto7376_0260 | PFAM: Urease, gamma subunit; TIGRFAM: urease, gamma subunit; COGs: COG0831 Urea amidohydrolase (urease) gamma subunit; HAMAP: Urease, gamma subunit; InterPro IPR002026:IPR012010; KEGG: ter:Tery_0746 urease, gamma subunit; PFAM: Urease, alpha/gamma subunit; PRIAM: Urease; SPTR: Urease subunit gamma; TIGRFAM: Urease, alpha/gamma subunit; Belongs to the urease gamma subunit family. | Hypothetical protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. | 0.699 |
| ureA | ureB | Lepto7376_0264 | Lepto7376_0263 | PFAM: Urease, gamma subunit; TIGRFAM: urease, gamma subunit; COGs: COG0831 Urea amidohydrolase (urease) gamma subunit; HAMAP: Urease, gamma subunit; InterPro IPR002026:IPR012010; KEGG: ter:Tery_0746 urease, gamma subunit; PFAM: Urease, alpha/gamma subunit; PRIAM: Urease; SPTR: Urease subunit gamma; TIGRFAM: Urease, alpha/gamma subunit; Belongs to the urease gamma subunit family. | PFAM: Urease beta subunit; TIGRFAM: urease, beta subunit; COGs: COG0832 Urea amidohydrolase (urease) beta subunit; HAMAP: Urease, beta subunit; InterPro IPR002019; KEGG: ter:Tery_0747 urease subunit beta; PFAM: Urease, beta subunit; PRIAM: Urease; SPTR: Urease subunit beta; TIGRFAM: Urease, beta subunit; Belongs to the urease beta subunit family. | 0.999 |
| ureA | ureC | Lepto7376_0264 | Lepto7376_0258 | PFAM: Urease, gamma subunit; TIGRFAM: urease, gamma subunit; COGs: COG0831 Urea amidohydrolase (urease) gamma subunit; HAMAP: Urease, gamma subunit; InterPro IPR002026:IPR012010; KEGG: ter:Tery_0746 urease, gamma subunit; PFAM: Urease, alpha/gamma subunit; PRIAM: Urease; SPTR: Urease subunit gamma; TIGRFAM: Urease, alpha/gamma subunit; Belongs to the urease gamma subunit family. | PFAM: Urease alpha-subunit, N-terminal domain; Amidohydrolase family; TIGRFAM: urease, alpha subunit; COGs: COG0804 Urea amidohydrolase (urease) alpha subunit; HAMAP: Urease, alpha subunit; InterPro IPR005848:IPR011612:IPR006680; KEGG: ter:Tery_0752 urease subunit alpha; PFAM: Amidohydrolase 1; Urease alpha-subunit, N-terminal; PRIAM: Urease; SPTR: Urease subunit alpha; TIGRFAM: Urease, alpha subunit. | 0.999 |