Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFY37309.1RNA polymerase, sigma subunit, RpsC/SigC; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (396 aa)    
Predicted Functional Partners:
sigA
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
     
  0.911
AFY38161.1
PFAM: MerR family regulatory protein; Bacterial transcription activator, effector binding domain; COGs: COG0789 transcriptional regulator protein; InterPro IPR000551:IPR010499; KEGG: ana:all0345 transcriptional regulator; PFAM: HTH transcriptional regulator, MerR; Bacterial transcription activator, effector binding; SMART: HTH transcriptional regulator, MerR; SPTR: Transcriptional activator ligand binding domain protein.
  
 
 0.841
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 0.797
AFY37094.1
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
     
  0.781
AFY38131.1
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
     
  0.781
AFY39428.1
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
     
  0.781
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 
  
 0.777
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 0.774
AFY39216.1
GTP-binding protein LepA; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; GTP-binding protein LepA C-terminus; Elongation factor Tu GTP binding domain; TIGRFAM: GTP-binding protein LepA; small GTP-binding protein domain; COGs: COG0481 Membrane GTPase LepA; HAMAP: GTP-binding protein LepA; InterProIPR005225:IPR006297:IPR000795:IPR004161:IPR 000640:IPR013842; KEGG: syp:SYNPCC7002_A2421 GTP-binding protein LepA; PFAM: GTP-binding protein LepA, C-terminal; Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation f [...]
 
 
 0.739
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 0.691
Your Current Organism:
Leptolyngbya sp. PCC7376
NCBI taxonomy Id: 111781
Other names: Enugrolinea bermudensis PCC 7376, L. sp. PCC 7376, Leptolyngbya PCC7376, Leptolyngbya sp. PCC 7376
Server load: low (28%) [HD]