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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
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AFY38273.12-hydroxy-3-oxopropionate reductase; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase; COGs: COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase; InterPro IPR006115; KEGG: syp:SYNPCC7002_A2814 3-hydroxyacid dehydrogenase; PFAM: 6-phosphogluconate dehydrogenase, NAD-binding; PRIAM: 2-hydroxy-3-oxopropionate reductase; SPTR: 3-hydroxyacid dehydrogenase. (285 aa)    
Predicted Functional Partners:
AFY40448.1
2-hydroxy-3-oxopropionate reductase; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase; COGs: COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase; InterPro IPR006115; KEGG: syp:SYNPCC7002_A1558 3-hydroxyisobutyrate dehydrogenase; PFAM: 6-phosphogluconate dehydrogenase, NAD-binding; PRIAM: 2-hydroxy-3-oxopropionate reductase; SPTR: 3-hydroxyisobutyrate dehydrogenase.
  
  
 
0.924
AFY36660.1
Quinone oxidoreductase, YhdH/YhfP family; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: putative quinone oxidoreductase, YhdH/YhfP family; COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR014188:IPR013154:IPR013149; KEGG: nha:Nham_3502 alcohol dehydrogenase GroES-like protein; PFAM: Alcohol dehydrogenase, zinc-binding; Alcohol dehydrogenase GroES-like; SPTR: Alcohol dehydrogenase GroES-like; TIGRFAM: Quinone oxidoreductase putative, YhdH/YhfP.
  
  
  0.823
AFY36540.1
PFAM: Citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; COGs: COG0372 Citrate synthase; InterPro IPR011278:IPR002020; KEGG: syp:SYNPCC7002_A2623 citrate synthase; PFAM: Citrate synthase-like; PRIAM: Citrate (Si)-synthase; SPTR: 2-methylcitrate synthase/citrate synthase II; TIGRFAM: 2-methylcitrate synthase/citrate synthase type I; Belongs to the citrate synthase family.
  
 
 0.822
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.817
AFY36802.1
PFAM: Glycine radical; Pyruvate formate lyase; TIGRFAM: formate acetyltransferase 1; COGs: COG1882 Pyruvate-formate lyase; InterPro IPR005949:IPR004184:IPR001150; KEGG: tel:tll0990 formate acetyltransferase; PFAM: Pyruvate formate-lyase, PFL; Formate C-acetyltransferase glycine radical; PRIAM: Formate C-acetyltransferase; SPTR: Formate acetyltransferase; TIGRFAM: Formate acetyltransferase.
     
  0.800
AFY38272.1
PFAM: Carbohydrate-selective porin, OprB family; S-layer homology domain; InterPro IPR001119:IPR007049; KEGG: syp:SYNPCC7002_A2813 S-layer like protein; porin; PFAM: Carbohydrate-selective porin OprB; S-layer homology domain; SPTR: S-layer like protein; probable porin; TC 1.B.23; Belongs to the OprB family.
  
    0.505
AFY36804.1
PFAM: Aldehyde dehydrogenase family; Iron-containing alcohol dehydrogenase; COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR015590:IPR001670; KEGG: amr:AM1_0442 bifunctional acetaldehyde-CoA/alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, iron-type; Aldehyde dehydrogenase; PRIAM: Acetaldehyde dehydrogenase (acetylating); SPTR: Aldehyde-alcohol dehydrogenase; alcohol dehydrogenase AdhE; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
  
 0.502
AFY39676.1
PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterPro IPR006176:IPR006108:IPR001753; KEGG: cyn:Cyan7425_3065 3-hydroxyacyl-CoA dehydrogenase NAD-binding; PFAM: 3-hydroxyacyl-CoA dehydrogenase, NAD binding; 3-hydroxyacyl-CoA dehydrogenase, C-terminal; Crotonase, core; PRIAM: 3-hydroxyacyl-CoA dehydrogenase., Enoyl-CoA hydratase; SPTR: 3-hydroxyacyl-CoA dehydrogenase NAD-binding.
  
  
 0.492
Your Current Organism:
Leptolyngbya sp. PCC7376
NCBI taxonomy Id: 111781
Other names: Enugrolinea bermudensis PCC 7376, L. sp. PCC 7376, Leptolyngbya PCC7376, Leptolyngbya sp. PCC 7376
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