Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AFY38311.1PFAM: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; COGs: COG1466 DNA polymerase III delta subunit; InterPro IPR010372:IPR005790; KEGG: syp:SYNPCC7002_A1567 DNA polymerase III subunit delta; PFAM: DNA polymerase III, delta; SPTR: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit. (326 aa)    
Predicted Functional Partners:
AFY39718.1
DNA polymerase III, subunits gamma and tau; PFAM: ATPase family associated with various cellular activities (AAA); DNA polymerase III subunits gamma and tau domain III; TIGRFAM: DNA polymerase III, subunit gamma and tau; COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR012763:IPR003593:IPR003959; KEGG: syp:SYNPCC7002_A1704 DNA-directed DNA polymerase III chain DnaX; PFAM: ATPase, AAA-type, core; SMART: ATPase, AAA+ type, core; SPTR: DNA-directed DNA polymerase III chain dnaX; TIGRFAM: DNA polymerase III, subunit gamma/ tau.
 
 
 0.999
AFY40507.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
 
 0.999
AFY39526.1
DNA polymerase III, delta prime subunit; PFAM: ATPase family associated with various cellular activities (AAA); TIGRFAM: DNA polymerase III, delta' subunit; COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR004622; KEGG: syp:SYNPCC7002_A1256 DNA polymerase III subunit delta'; SPTR: DNA polymerase III delta' subunit; TIGRFAM: DNA polymerase III, delta prime subunit.
  
 
 0.998
AFY38103.1
PFAM: OB-fold nucleic acid binding domain; TIGRFAM: intein C-terminal splicing region; COGs: COG0587 DNA polymerase III alpha subunit; InterPro IPR004365:IPR006141; KEGG: syp:SYNPCC7002_A2384 DNA polymerase III subunit alpha; PFAM: Nucleic acid binding, OB-fold, tRNA/helicase-type; SPTR: DNA polymerase III alpha subunit.
  
 0.985
AFY39012.1
PFAM: Bacterial DNA polymerase III alpha subunit; PHP domain; TIGRFAM: intein N-terminal splicing region; DNA-directed DNA polymerase III (polc); COGs: COG0587 DNA polymerase III alpha subunit; InterProIPR004805:IPR006141:IPR004013:IPR011708:IPR 003141:IPR003587; KEGG: syp:SYNPCC7002_A1408 DNA polymerase III subunit alpha; PFAM: Bacterial DNA polymerase III, alpha subunit; PHP, C-terminal; PRIAM: DNA-directed DNA polymerase; SMART: Polymerase/histidinol phosphatase, N-terminal; Hedgehog/intein hint, N-terminal; SPTR: DNA polymerase III alpha subunit; TIGRFAM: DNA polymerase III, alpha [...]
  
 0.985
AFY39014.1
PFAM: PHP domain; COGs: COG0587 DNA polymerase III alpha subunit; InterPro IPR004013; KEGG: syp:SYNPCC7002_A1408 DNA polymerase III subunit alpha; PFAM: PHP, C-terminal; SPTR: DNA polymerase III alpha subunit.
  
 0.864
AFY40518.1
Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
   
 0.811
AFY38161.1
PFAM: MerR family regulatory protein; Bacterial transcription activator, effector binding domain; COGs: COG0789 transcriptional regulator protein; InterPro IPR000551:IPR010499; KEGG: ana:all0345 transcriptional regulator; PFAM: HTH transcriptional regulator, MerR; Bacterial transcription activator, effector binding; SMART: HTH transcriptional regulator, MerR; SPTR: Transcriptional activator ligand binding domain protein.
    
  0.766
AFY37783.1
PFAM: MerR family regulatory protein; MerR, DNA binding; COGs: COG0789 transcriptional regulator protein; InterPro IPR000551:IPR015358; KEGG: syp:SYNPCC7002_A0131 MerR family transcriptional regulator; PFAM: Transcription regulator MerR, DNA binding; HTH transcriptional regulator, MerR; SMART: HTH transcriptional regulator, MerR; SPTR: Transcriptional regulator, MerR family.
    
  0.765
AFY38387.1
Recombination protein MgsA; PFAM: MgsA AAA+ ATPase C terminal; ATPase family associated with various cellular activities (AAA); COGs: COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; InterPro IPR003959:IPR003593; KEGG: ava:Ava_B0112 recombination factor protein RarA/unknown domain fusion protein; PFAM: ATPase, AAA-type, core; SMART: ATPase, AAA+ type, core; SPTR: Recombination protein MgsA.
    
  0.738
Your Current Organism:
Leptolyngbya sp. PCC7376
NCBI taxonomy Id: 111781
Other names: Enugrolinea bermudensis PCC 7376, L. sp. PCC 7376, Leptolyngbya PCC7376, Leptolyngbya sp. PCC 7376
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