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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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AFY39131.1Diguanylate cyclase; PFAM: CBS domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160:IPR000644; KEGG: syp:SYNPCC7002_A1499 GGDEF domain-containing protein; PFAM: Diguanylate cyclase, predicted; Cystathionine beta-synthase, core; SMART: Diguanylate cyclase, predicted; Cystathionine beta-synthase, core; SPTR: GGDEF domain protein; TIGRFAM: Diguanylate cyclase, predicted. (493 aa)    
Predicted Functional Partners:
AFY37229.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain; GGDEF domain; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG2200 FOG: EAL domain; InterPro IPR000160:IPR001633:IPR000014; KEGG: npu:Npun_F5467 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; SPTR: Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) (Modula [...]
 
 
 0.830
AFY38499.1
Diguanylate phosphodiesterase; PFAM: EAL domain; Cyclic nucleotide-binding domain; COGs: COG2200 FOG: EAL domain; InterPro IPR000595:IPR001633; KEGG: syn:slr0842 hypothetical protein; PFAM: Diguanylate phosphodiesterase, predicted; Cyclic nucleotide-binding; SMART: Diguanylate phosphodiesterase, predicted; Cyclic nucleotide-binding; SPTR: Slr0842 protein.
 
 0.823
AFY36748.1
PFAM: EAL domain; Response regulator receiver domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; COGs: COG2200 FOG: EAL domain; InterPro IPR001789:IPR000160:IPR001633; KEGG: syp:SYNPCC7002_A2364 two-component response regulator; PFAM: Diguanylate phosphodiesterase, predicted; Signal transduction response regulator, receiver domain; Diguanylate cyclase, predicted; SMART: Diguanylate phosphodiesterase, predicted; Signal transduction response regulator, receiver domain; Diguanylate cyclase, predicted; SPTR: Two-component response regulator; GGDEF domain protein; TIGRFAM: D [...]
 
  
 0.808
AFY37359.1
PFAM: EAL domain; GGDEF domain; Response regulator receiver domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterPro IPR001789:IPR000160:IPR001633; KEGG: syp:SYNPCC7002_A2869 sensory box/GGDEF family protein; PFAM: Diguanylate phosphodiesterase, predicted; Signal transduction response regulator, receiver domain; Diguanylate cyclase, predicted; SMART: Diguanylate phosphodiesterase, predicted; Signal transduction response regulator, receiver domain; Diguanylate cyclase, predicted; SPTR: [...]
 
  
 0.805
AFY40405.1
Diguanylate cyclase/phosphodiesterase with Chase sensor; PFAM: EAL domain; CHASE2 domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterPro IPR000160:IPR001633:IPR007890; KEGG: cyc:PCC7424_1893 diguanylate cyclase/phosphodiesterase with CHASE sensor; PFAM: Diguanylate phosphodiesterase, predicted; CHASE2; Diguanylate cyclase, predicted; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; SPTR: Diguanylate cyclase/phosphodiesterase with Chase s [...]
 
    0.801
AFY39189.1
PFAM: EAL domain; GGDEF domain; Response regulator receiver domain; COGs: COG2200 FOG: EAL domain; InterPro IPR001789:IPR000160:IPR001633; KEGG: cyc:PCC7424_2022 response regulator receiver modulated diguanylate cyclase/phosphodiesterase; PFAM: Diguanylate phosphodiesterase, predicted; Signal transduction response regulator, receiver domain; Diguanylate cyclase, predicted; SMART: Diguanylate phosphodiesterase, predicted; Signal transduction response regulator, receiver domain; Diguanylate cyclase, predicted; SPTR: Response regulator receiver modulated diguanylate cyclase/phosphodiesterase.
 
  
 0.799
AFY37537.1
PFAM: EAL domain; GGDEF domain; Response regulator receiver domain; COGs: COG2200 FOG: EAL domain; InterPro IPR001789:IPR000160:IPR001633; KEGG: cyc:PCC7424_2022 response regulator receiver modulated diguanylate cyclase/phosphodiesterase; PFAM: Diguanylate phosphodiesterase, predicted; Signal transduction response regulator, receiver domain; SMART: Diguanylate phosphodiesterase, predicted; Signal transduction response regulator, receiver domain; Diguanylate cyclase, predicted; SPTR: Hybrid signal transduction histidine kinase and diguanylatecyclase/phosphodiesterase.
 
  
 0.797
AFY39396.1
Diguanylate cyclase; PFAM: GGDEF domain; GAF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160:IPR003018; KEGG: npu:Npun_F1553 diguanylate cyclase with PAS/PAC and GAF sensors; PFAM: Diguanylate cyclase, predicted; GAF; SMART: Diguanylate cyclase, predicted; GAF; SPTR: Diguanylate cyclase with PAS/PAC and GAF sensors; TIGRFAM: Diguanylate cyclase, predicted.
 
  
 0.786
AFY38811.1
Diguanylate phosphodiesterase; PFAM: EAL domain; COGs: COG2200 FOG: EAL domain; InterPro IPR001633; KEGG: syp:SYNPCC7002_A2654 EAL domain-containing protein; PFAM: Diguanylate phosphodiesterase, predicted; SMART: Diguanylate phosphodiesterase, predicted; SPTR: EAL domain protein.
 
    0.783
AFY37557.1
Diguanylate phosphodiesterase; PFAM: Phosphotransferase system, EIIC; EAL domain; TIGRFAM: PTS system, lactose/cellobiose family IIC component; COGs: COG1455 Phosphotransferase system cellobiose-specific component IIC; InterPro IPR001633:IPR003352; KEGG: amr:AM1_2089 phosphotransferase system, lactose/cellobiose IIC component, putative; PFAM: Diguanylate phosphodiesterase, predicted; Phosphotransferase system, EIIC; SMART: Diguanylate phosphodiesterase, predicted; SPTR: Phosphotransferase system, lactose/cellobiose IIC component, putative.
 
    0.771
Your Current Organism:
Leptolyngbya sp. PCC7376
NCBI taxonomy Id: 111781
Other names: Enugrolinea bermudensis PCC 7376, L. sp. PCC 7376, Leptolyngbya PCC7376, Leptolyngbya sp. PCC 7376
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