| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AFY38812.1 | AFY39878.1 | Lepto7376_2538 | Lepto7376_3702 | PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR006366:IPR000878:IPR003754; KEGG: syp:SYNPCC7002_A1192 uroporphyrin-III synthase/methyltransferase; PFAM: Tetrapyrrole methylase; Tetrapyrrole biosynthesis, uroporphyrinogen III synthase; PRIAM: Uroporphyrinogen-III C-methyltransferase., Uroporphyrinogen-III synthase; SPTR: Uroporphyrin-III synthase/methyltransferase; TIGRFAM: Uroporphyrin-III C-methyltransferase, C-terminal; uroporphyrinogen-III s [...] | Hypothetical protein; PFAM: Phosphoadenosine phosphosulfate reductase family; KEGG: mau:Micau_4141 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.647 |
| AFY38812.1 | cysC | Lepto7376_2538 | Lepto7376_4223 | PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR006366:IPR000878:IPR003754; KEGG: syp:SYNPCC7002_A1192 uroporphyrin-III synthase/methyltransferase; PFAM: Tetrapyrrole methylase; Tetrapyrrole biosynthesis, uroporphyrinogen III synthase; PRIAM: Uroporphyrinogen-III C-methyltransferase., Uroporphyrinogen-III synthase; SPTR: Uroporphyrin-III synthase/methyltransferase; TIGRFAM: Uroporphyrin-III C-methyltransferase, C-terminal; uroporphyrinogen-III s [...] | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.727 |
| AFY39453.1 | AFY39878.1 | Lepto7376_3225 | Lepto7376_3702 | PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS; InterPro IPR010035:IPR003749; KEGG: syp:SYNPCC7002_A0278 thiamine biosynthesis protein ThiS; PFAM: ThiamineS; SPTR: Thiamine biosynthesis protein ThiS; TIGRFAM: ThiS, thiamine-biosynthesis. | Hypothetical protein; PFAM: Phosphoadenosine phosphosulfate reductase family; KEGG: mau:Micau_4141 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.744 |
| AFY39453.1 | glgC | Lepto7376_3225 | Lepto7376_4505 | PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS; InterPro IPR010035:IPR003749; KEGG: syp:SYNPCC7002_A0278 thiamine biosynthesis protein ThiS; PFAM: ThiamineS; SPTR: Thiamine biosynthesis protein ThiS; TIGRFAM: ThiS, thiamine-biosynthesis. | Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | 0.818 |
| AFY39870.1 | AFY39877.1 | Lepto7376_3694 | Lepto7376_3701 | KEGG: tva:TVAG_284550 hypothetical protein; SPTR: Putative uncharacterized protein. | MT-A70 family protein; PFAM: MT-A70; COGs: COG4725 Transcriptional activator adenine-specific DNA methyltransferase; InterPro IPR007757; KEGG: spj:MGAS2096_Spy1128 adenine-specific methyltransferase; PFAM: MT-A70; SPTR: Adenine-specific methyltransferase; Belongs to the MT-A70-like family. | 0.620 |
| AFY39870.1 | AFY39878.1 | Lepto7376_3694 | Lepto7376_3702 | KEGG: tva:TVAG_284550 hypothetical protein; SPTR: Putative uncharacterized protein. | Hypothetical protein; PFAM: Phosphoadenosine phosphosulfate reductase family; KEGG: mau:Micau_4141 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.620 |
| AFY39870.1 | AFY39879.1 | Lepto7376_3694 | Lepto7376_3703 | KEGG: tva:TVAG_284550 hypothetical protein; SPTR: Putative uncharacterized protein. | KEGG: hau:Haur_0198 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated. | 0.525 |
| AFY39870.1 | AFY39880.1 | Lepto7376_3694 | Lepto7376_3704 | KEGG: tva:TVAG_284550 hypothetical protein; SPTR: Putative uncharacterized protein. | PFAM: Virulence-associated protein E; COGs: COG5545 P-loop ATPase and inactivated derivatives; InterPro IPR007936; KEGG: cyc:PCC7424_0144 virulence-associated E family protein; PFAM: Virulence-associated E; SPTR: Virulence-associated E family protein. | 0.525 |
| AFY39870.1 | AFY39881.1 | Lepto7376_3694 | Lepto7376_3705 | KEGG: tva:TVAG_284550 hypothetical protein; SPTR: Putative uncharacterized protein. | HNH endonuclease; InterPro IPR002711; KEGG: syp:SYNPCC7002_A1878 hypothetical protein; PFAM: HNH endonuclease; SPTR: Putative uncharacterized protein. | 0.525 |
| AFY39870.1 | AFY39882.1 | Lepto7376_3694 | Lepto7376_3706 | KEGG: tva:TVAG_284550 hypothetical protein; SPTR: Putative uncharacterized protein. | Hypothetical protein; KEGG: hmg:100206072 similar to putative sulfate transporter of the SLC26A11 family. | 0.525 |
| AFY39877.1 | AFY39870.1 | Lepto7376_3701 | Lepto7376_3694 | MT-A70 family protein; PFAM: MT-A70; COGs: COG4725 Transcriptional activator adenine-specific DNA methyltransferase; InterPro IPR007757; KEGG: spj:MGAS2096_Spy1128 adenine-specific methyltransferase; PFAM: MT-A70; SPTR: Adenine-specific methyltransferase; Belongs to the MT-A70-like family. | KEGG: tva:TVAG_284550 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.620 |
| AFY39877.1 | AFY39878.1 | Lepto7376_3701 | Lepto7376_3702 | MT-A70 family protein; PFAM: MT-A70; COGs: COG4725 Transcriptional activator adenine-specific DNA methyltransferase; InterPro IPR007757; KEGG: spj:MGAS2096_Spy1128 adenine-specific methyltransferase; PFAM: MT-A70; SPTR: Adenine-specific methyltransferase; Belongs to the MT-A70-like family. | Hypothetical protein; PFAM: Phosphoadenosine phosphosulfate reductase family; KEGG: mau:Micau_4141 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.776 |
| AFY39877.1 | AFY39879.1 | Lepto7376_3701 | Lepto7376_3703 | MT-A70 family protein; PFAM: MT-A70; COGs: COG4725 Transcriptional activator adenine-specific DNA methyltransferase; InterPro IPR007757; KEGG: spj:MGAS2096_Spy1128 adenine-specific methyltransferase; PFAM: MT-A70; SPTR: Adenine-specific methyltransferase; Belongs to the MT-A70-like family. | KEGG: hau:Haur_0198 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated. | 0.648 |
| AFY39877.1 | AFY39880.1 | Lepto7376_3701 | Lepto7376_3704 | MT-A70 family protein; PFAM: MT-A70; COGs: COG4725 Transcriptional activator adenine-specific DNA methyltransferase; InterPro IPR007757; KEGG: spj:MGAS2096_Spy1128 adenine-specific methyltransferase; PFAM: MT-A70; SPTR: Adenine-specific methyltransferase; Belongs to the MT-A70-like family. | PFAM: Virulence-associated protein E; COGs: COG5545 P-loop ATPase and inactivated derivatives; InterPro IPR007936; KEGG: cyc:PCC7424_0144 virulence-associated E family protein; PFAM: Virulence-associated E; SPTR: Virulence-associated E family protein. | 0.692 |
| AFY39877.1 | AFY39881.1 | Lepto7376_3701 | Lepto7376_3705 | MT-A70 family protein; PFAM: MT-A70; COGs: COG4725 Transcriptional activator adenine-specific DNA methyltransferase; InterPro IPR007757; KEGG: spj:MGAS2096_Spy1128 adenine-specific methyltransferase; PFAM: MT-A70; SPTR: Adenine-specific methyltransferase; Belongs to the MT-A70-like family. | HNH endonuclease; InterPro IPR002711; KEGG: syp:SYNPCC7002_A1878 hypothetical protein; PFAM: HNH endonuclease; SPTR: Putative uncharacterized protein. | 0.649 |
| AFY39877.1 | AFY39882.1 | Lepto7376_3701 | Lepto7376_3706 | MT-A70 family protein; PFAM: MT-A70; COGs: COG4725 Transcriptional activator adenine-specific DNA methyltransferase; InterPro IPR007757; KEGG: spj:MGAS2096_Spy1128 adenine-specific methyltransferase; PFAM: MT-A70; SPTR: Adenine-specific methyltransferase; Belongs to the MT-A70-like family. | Hypothetical protein; KEGG: hmg:100206072 similar to putative sulfate transporter of the SLC26A11 family. | 0.648 |
| AFY39878.1 | AFY38812.1 | Lepto7376_3702 | Lepto7376_2538 | Hypothetical protein; PFAM: Phosphoadenosine phosphosulfate reductase family; KEGG: mau:Micau_4141 hypothetical protein; SPTR: Putative uncharacterized protein. | PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR006366:IPR000878:IPR003754; KEGG: syp:SYNPCC7002_A1192 uroporphyrin-III synthase/methyltransferase; PFAM: Tetrapyrrole methylase; Tetrapyrrole biosynthesis, uroporphyrinogen III synthase; PRIAM: Uroporphyrinogen-III C-methyltransferase., Uroporphyrinogen-III synthase; SPTR: Uroporphyrin-III synthase/methyltransferase; TIGRFAM: Uroporphyrin-III C-methyltransferase, C-terminal; uroporphyrinogen-III s [...] | 0.647 |
| AFY39878.1 | AFY39453.1 | Lepto7376_3702 | Lepto7376_3225 | Hypothetical protein; PFAM: Phosphoadenosine phosphosulfate reductase family; KEGG: mau:Micau_4141 hypothetical protein; SPTR: Putative uncharacterized protein. | PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS; InterPro IPR010035:IPR003749; KEGG: syp:SYNPCC7002_A0278 thiamine biosynthesis protein ThiS; PFAM: ThiamineS; SPTR: Thiamine biosynthesis protein ThiS; TIGRFAM: ThiS, thiamine-biosynthesis. | 0.744 |
| AFY39878.1 | AFY39870.1 | Lepto7376_3702 | Lepto7376_3694 | Hypothetical protein; PFAM: Phosphoadenosine phosphosulfate reductase family; KEGG: mau:Micau_4141 hypothetical protein; SPTR: Putative uncharacterized protein. | KEGG: tva:TVAG_284550 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.620 |
| AFY39878.1 | AFY39877.1 | Lepto7376_3702 | Lepto7376_3701 | Hypothetical protein; PFAM: Phosphoadenosine phosphosulfate reductase family; KEGG: mau:Micau_4141 hypothetical protein; SPTR: Putative uncharacterized protein. | MT-A70 family protein; PFAM: MT-A70; COGs: COG4725 Transcriptional activator adenine-specific DNA methyltransferase; InterPro IPR007757; KEGG: spj:MGAS2096_Spy1128 adenine-specific methyltransferase; PFAM: MT-A70; SPTR: Adenine-specific methyltransferase; Belongs to the MT-A70-like family. | 0.776 |