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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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AFY40170.1O-succinylbenzoic acid (OSB) synthetase; PFAM: Mandelate racemase / muconate lactonizing enzyme, C-terminal domain; TIGRFAM: o-succinylbenzoate synthase; COGs: COG4948 L-alanine-DL-glutamate epimerase; InterPro IPR010196:IPR013342; KEGG: syp:SYNPCC7002_A2642 O-succinylbenzoate synthase; PFAM: Mandelate racemase/muconate lactonizing enzyme, C-terminal; SPTR: O-succinylbenzoic acid (OSB) synthetase; TIGRFAM: O-succinylbenzoic acid (OSB) synthetase, gamma proteobacteria/archaea. (310 aa)    
Predicted Functional Partners:
AFY36562.1
o-succinylbenzoate--CoA ligase; PFAM: AMP-binding enzyme; COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: syp:SYNPCC7002_A1250 O-succinylbenzoic acid--CoA ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: o-succinylbenzoate--CoA ligase; SPTR: O-succinylbenzoyl-CoA synthetase.
 
 
  0.948
menD
2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
 
   
 0.770
AFY40171.1
KEGG: afv:AFLA_116800 hypothetical protein; SPTR: Synaptic vesicle transporter SVOP and related transporters.
       0.693
menB
1,4-Dihydroxy-2-naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA).
 
   
 0.681
AFY39778.1
Isochorismate synthase; PFAM: chorismate binding enzyme; TIGRFAM: isochorismate synthases; COGs: COG1169 Isochorismate synthase; InterPro IPR015890:IPR004561; KEGG: syp:SYNPCC7002_A0999 isochorismate synthase; PFAM: Chorismate binding, C-terminal; PRIAM: Isochorismate synthase; SPTR: Isochorismate synthase; TIGRFAM: Isochorismate synthase.
 
   
 0.652
menA
1,4-dihydroxy-2-naphthoate phytyltransferase; Involved in the synthesis of phylloquinone (vitamin K1). Catalyzes the transfer of a prenyl chain to 2-carboxy-1,4- naphthoquinone; Belongs to the MenA family. Type 2 subfamily.
 
   
 0.635
AFY39601.1
1,4-dihydroxy-2-naphthoyl-CoA hydrolase; Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in phylloquinone (vitamin K1) biosynthesis; Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. DHNA-CoA hydrolase subfamily.
 
   
 0.540
AFY39349.1
o-succinylbenzoate--CoA ligase; PFAM: AMP-binding enzyme; COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: str:Sterm_1953 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: o-succinylbenzoate--CoA ligase; SPTR: AMP-dependent synthetase and ligase.
  
 
  0.516
AFY39124.1
COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073; KEGG: syp:SYNPCC7002_A1594 alpha/beta fold family hydrolase; PFAM: Alpha/beta hydrolase fold-1; SPTR: Hydrolase, alpha/beta fold family.
    
 0.512
AFY40172.1
PFAM: Miro-like protein; TIGRFAM: small GTP-binding protein domain; COGs: COG4886 Leucine-rich repeat (LRR) protein; InterPro IPR003591:IPR005225:IPR001611:IPR013684; KEGG: ter:Tery_3798 small GTP-binding protein; PFAM: MIRO-like; Leucine-rich repeat; SPTR: Small GTP-binding protein; TIGRFAM: Small GTP-binding protein.
       0.499
Your Current Organism:
Leptolyngbya sp. PCC7376
NCBI taxonomy Id: 111781
Other names: Enugrolinea bermudensis PCC 7376, L. sp. PCC 7376, Leptolyngbya PCC7376, Leptolyngbya sp. PCC 7376
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