STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORA98197.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (258 aa)    
Predicted Functional Partners:
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
  
  
 0.827
ORA98215.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.788
ORA98199.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.788
RdgB
Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
    0.779
clpS
ATP-dependent Clp protease adapter ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.
       0.758
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
     
 0.657
ORA98216.1
Rhomboid family intramembrane serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.655
ORB00573.1
Crp/Fnr family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.600
QcrB
Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.599
PncB
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
     
 0.585
Your Current Organism:
Mycolicibacter minnesotensis
NCBI taxonomy Id: 1118379
Other names: DSM 45633, JCM 17932, M. minnesotensis, Mycobacterium minnesotense, Mycobacterium minnesotense Hannigan et al. 2013, Mycobacterium sp. DL150B, Mycobacterium sp. DL184, Mycobacterium sp. DL189, Mycobacterium sp. DL215A, Mycobacterium sp. DL228B, Mycobacterium sp. DL47, Mycobacterium sp. DL477, Mycobacterium sp. DL482, Mycobacterium sp. DL49, Mycobacterium sp. DL604, Mycobacterium sp. DL630, Mycobacterium sp. DL678A, Mycobacterium sp. DL685, Mycolicibacter minnesotensis (Hannigan et al. 2013) Gupta et al. 2018, NCCB 100399, strain DL49
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