STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H257_11423Lipoyl-binding domain-containing protein. (228 aa)    
Predicted Functional Partners:
B5M09_012604
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 0.951
H257_08274
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
   
 0.949
H257_15577
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 0.915
H257_06178
2-oxoisovalerate dehydrogenase subunit beta, mitochondrial.
  
 0.914
H257_15299
Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component.
  
 0.907
H257_00390
Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component, variant 1.
  
 0.907
B5M09_009678
Dihydrolipoyl dehydrogenase.
  
 0.904
H257_12914
Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component.
  
 0.904
H257_07450
Uncharacterized protein.
  
 0.904
H257_01186
Uncharacterized protein.
  
 0.904
Your Current Organism:
Aphanomyces astaci
NCBI taxonomy Id: 112090
Other names: A. astaci
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.