STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H257_10135PHD-type domain-containing protein. (464 aa)    
Predicted Functional Partners:
H257_11344
Ubiquitin-60S ribosomal protein L40.
    
  0.689
H257_15813
Histone-binding protein RBBP4.
    
 0.667
B5M09_000624
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.644
H257_09596
Uncharacterized protein.
    
 0.644
H257_06781
B30.2/SPRY domain-containing protein.
    
 0.638
H257_04848
BRCT domain-containing protein.
    
 0.615
H257_13731
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
   
 0.611
B5M09_004466
Histone H2B; Belongs to the histone H2B family.
    
 0.587
B5M09_000627
Histone H2B; Belongs to the histone H2B family.
    
 0.587
H257_07829
Uncharacterized protein.
    
 0.587
Your Current Organism:
Aphanomyces astaci
NCBI taxonomy Id: 112090
Other names: A. astaci
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.