STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H257_09117Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family. (300 aa)    
Predicted Functional Partners:
B5M09_006070
Eukaryotic translation initiation factor 5A.
  
 0.982
B5M09_010163
Translation elongation factor P.
  
 0.915
H257_02025
Deoxyhypusine synthase.
   
 0.840
B5M09_010165
Triosephosphate isomerase.
     
 0.790
B5M09_002247
WD_REPEATS_REGION domain-containing protein.
   
    0.756
H257_15577
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
   
 
 0.755
H257_02211
Sulfatase domain-containing protein.
  
 
  0.749
B5M09_001961
Fructose-bisphosphate aldolase, class II.
     
 0.742
H257_02858
Suf domain-containing protein.
     
 0.737
H257_16469
OTCace domain-containing protein; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
   
 
 0.726
Your Current Organism:
Aphanomyces astaci
NCBI taxonomy Id: 112090
Other names: A. astaci
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