STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H257_05177ERCC4 domain-containing protein. (559 aa)    
Predicted Functional Partners:
DYB26_001434
Helicase ATP-binding domain-containing protein.
    
 0.999
H257_10110
Uncharacterized protein.
    
 0.999
H257_01143
Uncharacterized protein.
   
 0.964
H257_01816
Uncharacterized protein.
    
 0.955
H257_06457
Uncharacterized protein.
   
 0.950
H257_15346
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
    
 0.941
H257_03813
Replication protein A subunit.
    
 0.915
H257_03711
CMGC protein kinase.
   
 
 0.904
H257_04018
DNA repair protein.
    
 0.898
H257_13669
Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family.
   
 0.879
Your Current Organism:
Aphanomyces astaci
NCBI taxonomy Id: 112090
Other names: A. astaci
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