STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H257_004502-Hacid_dh_C domain-containing protein. (334 aa)    
Predicted Functional Partners:
H257_01767
Tryptophan synthase, alpha subunit; Belongs to the TrpA family.
  
 0.918
H257_00119
Tryptophan synthase, beta subunit.
  
 0.918
H257_10015
Malate synthase; Belongs to the malate synthase family.
    
 0.844
H257_05315
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.
  
 0.764
B5M09_001643
Phosphoserine phosphatase SerB.
  
 0.705
H257_01765
Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.
  
 
 0.682
H257_10923
Acetolactate synthase.
  
 
 0.670
B5M09_003717
Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.
   
 
 0.667
H257_02809
4-aminobutyrate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
   
 0.659
B5M09_004812
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 0.646
Your Current Organism:
Aphanomyces astaci
NCBI taxonomy Id: 112090
Other names: A. astaci
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