STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFB22457.1O-acetylhomoserine sulfhydrylase. (426 aa)    
Predicted Functional Partners:
metAA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
  
 
 0.886
SFA70646.1
5-methyltetrahydrofolate--homocysteine methyltransferase.
  
 
 0.854
SFB12611.1
Cystathionine gamma-synthase/cystathionine beta-lyase.
 
 
0.792
SFA88265.1
Serine O-acetyltransferase.
    
 0.770
rnfB
Electron transport complex, RnfABCDGE type, B subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
    
  0.748
SFA83172.1
Homoserine dehydrogenase.
  
 
 0.720
SFB26689.1
Cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 
 0.715
SFA78247.1
Threonine dehydratase.
   
 
  0.662
SFB39308.1
S-ribosylhomocysteine lyase /quorum-sensing autoinducer 2 (AI-2) synthesis protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
     
 0.659
SFA70379.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
    
 0.611
Your Current Organism:
Acetitomaculum ruminis
NCBI taxonomy Id: 1120918
Other names: A. ruminis DSM 5522, Acetitomaculum ruminis DSM 5522
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