STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFB26706.1DNA-binding transcriptional regulator, MerR family. (280 aa)    
Predicted Functional Partners:
SFB06831.1
Signal transduction histidine kinase.
   
 0.718
SFB18307.1
Signal transduction histidine kinase.
   
 0.715
SFB11261.1
Hypothetical protein.
  
 
 0.698
SFB11277.1
Hypothetical protein.
  
 
 0.698
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
  
 
 0.698
SFB20857.1
Glutamine synthetase.
  
 
 0.688
SFA70379.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
   
 
 0.679
SFB38614.1
Response regulator receiver domain-containing protein.
   
 
 0.670
SFB12798.1
Signal transduction histidine kinase.
   
 0.664
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.662
Your Current Organism:
Acetitomaculum ruminis
NCBI taxonomy Id: 1120918
Other names: A. ruminis DSM 5522, Acetitomaculum ruminis DSM 5522
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.