STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHE66553.18-oxoguanine deaminase. (448 aa)    
Predicted Functional Partners:
SHE66631.1
Xanthine dehydrogenase, molybdenum binding subunit apoprotein.
 
 
 0.815
SHE66654.1
Xanthine dehydrogenase small subunit.
 
  
  0.786
hutI
Imidazolonepropionase.
  
 
 0.707
SHF33009.1
Formiminoglutamase.
  
 
 0.697
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
     
 0.685
mtnP
Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
    
 0.682
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family.
   
  0.674
SHE54659.1
N-formylglutamate deformylase.
  
 
 0.664
SHE66386.1
Nucleoside-binding protein.
 
     0.625
SHE66410.1
Simple sugar transport system permease protein; Belongs to the binding-protein-dependent transport system permease family.
 
     0.623
Your Current Organism:
Acidocella aminolytica
NCBI taxonomy Id: 1120923
Other names: A. aminolytica 101 = DSM 11237, Acidocella aminolytica 101, Acidocella aminolytica 101 = DSM 11237, Acidocella aminolytica DSM 11237, Acidocella aminolytica DSM 11237 = 101
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