SCZ42037.1 protein (Afifella marina) - STRING interaction network

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Score

SCZ42037.1

Histidinol-phosphate aminotransferase. (366 aa)

Predicted Functional Partners:

hisD

0.996

hisB

0.996

hisH

0.975

hisF

0.968

cobQ

0.956

hisI

0.950

SCZ21611.1

0.944

hisA

0.905

SCZ39836.1

0.862

hisE

0.860

Your Current Organism:

Afifella marina

NCBI taxonomy Id: 1120955
Other names: A. marina DSM 2698, Afifella marina DSM 2698

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SCZ21611.1	SCZ42037.1	SAMN03080610_00290	SAMN03080610_02853	ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.	Histidinol-phosphate aminotransferase.	0.944
SCZ21611.1	hisA	SAMN03080610_00290	SAMN03080610_01916	ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.	1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase.	0.991
SCZ21611.1	hisB	SAMN03080610_00290	SAMN03080610_01913	ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.	Imidazoleglycerol-phosphate dehydratase.	0.985
SCZ21611.1	hisD	SAMN03080610_00290	SAMN03080610_00159	ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.	Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.	0.994
SCZ21611.1	hisE	SAMN03080610_00290	SAMN03080610_01919	ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.	phosphoribosyl-ATP pyrophosphatase.	0.995
SCZ21611.1	hisF	SAMN03080610_00290	SAMN03080610_01918	ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.	Cyclase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.	0.993
SCZ21611.1	hisH	SAMN03080610_00290	SAMN03080610_01915	ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.	Glutamine amidotransferase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.	0.985
SCZ21611.1	hisI	SAMN03080610_00290	SAMN03080610_03479	ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.	phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.	0.994
SCZ39836.1	SCZ42037.1	SAMN03080610_02553	SAMN03080610_02853	Prephenate dehydrogenase.	Histidinol-phosphate aminotransferase.	0.862
SCZ39836.1	hisB	SAMN03080610_02553	SAMN03080610_01913	Prephenate dehydrogenase.	Imidazoleglycerol-phosphate dehydratase.	0.505
SCZ42037.1	SCZ21611.1	SAMN03080610_02853	SAMN03080610_00290	Histidinol-phosphate aminotransferase.	ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.	0.944
SCZ42037.1	SCZ39836.1	SAMN03080610_02853	SAMN03080610_02553	Histidinol-phosphate aminotransferase.	Prephenate dehydrogenase.	0.862
SCZ42037.1	cobQ	SAMN03080610_02853	SAMN03080610_03410	Histidinol-phosphate aminotransferase.	Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.	0.956
SCZ42037.1	hisA	SAMN03080610_02853	SAMN03080610_01916	Histidinol-phosphate aminotransferase.	1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase.	0.905
SCZ42037.1	hisB	SAMN03080610_02853	SAMN03080610_01913	Histidinol-phosphate aminotransferase.	Imidazoleglycerol-phosphate dehydratase.	0.996
SCZ42037.1	hisD	SAMN03080610_02853	SAMN03080610_00159	Histidinol-phosphate aminotransferase.	Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.	0.996
SCZ42037.1	hisE	SAMN03080610_02853	SAMN03080610_01919	Histidinol-phosphate aminotransferase.	phosphoribosyl-ATP pyrophosphatase.	0.860
SCZ42037.1	hisF	SAMN03080610_02853	SAMN03080610_01918	Histidinol-phosphate aminotransferase.	Cyclase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.	0.968
SCZ42037.1	hisH	SAMN03080610_02853	SAMN03080610_01915	Histidinol-phosphate aminotransferase.	Glutamine amidotransferase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.	0.975
SCZ42037.1	hisI	SAMN03080610_02853	SAMN03080610_03479	Histidinol-phosphate aminotransferase.	phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.	0.950