STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrEUnannotated protein; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (185 aa)    
Predicted Functional Partners:
pyrF
Unannotated protein.
 
 
 0.998
pyrD
Unannotated protein; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
 0.997
pyrC
Unannotated protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
 
 
 0.980
pyrB
Unannotated protein; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
  
 0.971
carB
Unannotated protein; Belongs to the CarB family.
 
 
 0.962
carA
Unannotated protein; Belongs to the CarA family.
 
  
 0.953
pyrR
Unannotated protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
  
 
 0.900
prs
Unannotated protein; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 
 0.895
guaA
Unannotated protein; Catalyzes the synthesis of GMP from XMP.
 
 
 0.885
D8Y24_05310
Unannotated protein.
  
  
 0.790
Your Current Organism:
Agrococcus lahaulensis
NCBI taxonomy Id: 1120958
Other names: A. lahaulensis DSM 17612, Agrococcus lahaulensis DSM 17612
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